Detailed Biography:
C. Noel Bairey Merz, MD, holds the Irwin and Sheila Allen Chair in Women’s Heart Research, and is Director of the Barbra Streisand Women’s Heart Center, the Linda Joy Pollin Women’s Heart Health Program, the Erika J Glazer Women’s Heart Research Initiative, and the Preventive Cardiac Center at the Cedars-Sinai Heart Institute. She also is Professor of Medicine at Cedars-Sinai Medical Center.
Dr. Bairey Merz’s research interests include women and cardiovascular disease, mental stress and heart disease, preventive cardiology and the role of risk factors including stress management in reversing disease. A prolific lecturer and member of many professional organizations, Dr. Bairey Merz, has received numerous investigational grants and chairs the National Institutes of Health (NIH)-sponsored WISE (Women’s Ischemic Syndrome Evaluation) initiative. Dr. Bairey Merz has received numerous awards and honors, and her extensive scientific publication record spans 425+ scientific papers, 315+ abstracts, myriad book chapters, and countless peer-reviewed journals.
Dr. Bairey Merz earned her bachelor’s degree at the University of Chicago, her medical degree at Harvard University, and completed her residency at the University of California, San Francisco, where she served as Chief Medical Resident before completing fellowships in clinical cardiology and nuclear cardiology at Cedars-Sinai Medical Center.
A prolific lecturer, Dr. Bairey Merz, is a member of many professional organizations, including the American College of Cardiology (ACC), the American Heart Association (AHA), the Academy of Behavioral Medicine Research, the American Society of Preventive Cardiology, the Association of Academic Women's Health Programs, and the Association of Women's Heart Programs. She has served on the NHLBI Advisory Council, the Board of Trustees of the ACC, and is a past-chair of the ACC Publication, the Prevention of Cardiovascular Disease and the Cardiovascular Disease in Women committees. Other professional associations have included membership on the National Space Biomedical Research Institute Board of Scientific Counselors, the American Board of Internal Medicine (ABIM) Board of Examiners, Chair of the NIH-sponsored Bypass Angioplasty Revascularization Investigations 2 Diabetes (BARI-2D) Data Safety Monitoring Board (DSMB) and the ISCHEMIA Trial Steering Committee. She serves on the advisory boards of lay organizations, including WomenHeart and the Women’s Heart Alliance.
Dr. Bairey Merz has received numerous awards and honors, including the 2008 McCue Female Cardiologist of the Year Award, the 2005 Red Dress Award For Leadership in Cardiovascular Research in Women, the 2005 VHA Inc. Best Practices Awards for Special Achievement Award presented to an individual who has made an outstanding contribution to the field of health care, the 2005 Women of the 21st Century award from the Women's Guild of Cedars-Sinai Medical Center, and the 2006 Alvin P. Shapiro Award by Psychosomatic Society for excellence in clinical research.
Dr. Bairey Merz has appeared frequently in the media, recognized as an authority on the subject of heart disease. Her television appearances have included Good Morning America, NBC Dateline and 20/20. She has also been interviewed for articles published in The New York Times, Ladies Home Journal, US News & World Report and Working Woman Magazine, to name a few. Dr. Bairey Merz is currently a national spokesperson for the Women’s Heart Alliance PSA campaign, which seeks to raise awareness of heart disease in women.
Publications:
A selected list of publications:
Pacheco Christine, Wei Janet, Shufelt Chrisandra, C Hitzeman Tara, Cook-Wiens Galen, Pepine Carl J, Handberg Eileen, Anderson R David, Petersen John, Hong TingTing, M Shaw Robin, Bairey Merz C Noel
Association of coronary microvascular dysfunction and cardiac bridge
integrator 1, a cardiomyocyte dysfunction biomarker
Clinical cardiology,
2021; 44(11):
1586-1593.
Jalnapurkar Sawan, Landes Sofy, Wei Janet, Mehta Puja K, Shufelt Chrisandra, Minissian Margo, Pepine Carl J, Handberg Eileen, Cook-Wiens Galen, Sopko George, Bairey Merz C Noel
Coronary endothelial dysfunction appears to be a manifestation of a
systemic process: A report from the Women's Ischemia Syndrome
Evaluation - Coronary Vascular Dysfunction (WISE-CVD) study
PloS one,
2021; 16(9):
e0257184.
Quesada Odayme, Claggett Brian, Rodriguez Fatima, Cai Jianwen, Moncrieft Ashley E, Garcia Karin, Del Rios Rivera Marina, Hanna David B, Daviglus Martha L, Talavera Gregory A, Bairey Merz C Noel, Solomon Scott D, Cheng Susan, Bello Natalie A
Associations of Insulin Resistance With Systolic and Diastolic Blood
Pressure: A Study From the HCHS/SOL
Hypertension (Dallas, Tex. : 1979),
2021; 78(3):
716-725.
Handberg Eileen M, Merz C Noel Bairey, Cooper-Dehoff Rhonda M, Wei Janet, Conlon Michael, Lo Margaret C, Boden William, Frayne Susan M, Villines Todd, Spertus John A, Weintraub William, O'Malley Patrick, Chaitman Bernard, Shaw Leslee J, Budoff Matthew, Rogatko Andre, Pepine Carl J
Rationale and design of the Women's Ischemia Trial to Reduce Events in
Nonobstructive CAD (WARRIOR) trial
American heart journal,
2021; 237(9):
90-103.
Suppogu Nissi, Wei Janet, Quesada Odayme, Shufelt Chrisandra, Cook-Wiens Galen, Samuels Bruce, Petersen John W, Anderson R David, Handberg Eileen M, Pepine Carl J, Bairey Merz C Noel
Angina relates to coronary flow in women with ischemia and no
obstructive coronary artery disease
International journal of cardiology,
2021; 333(10292):
35-39.
Pacheco Christine, Boivin-Proulx Laurie-Anne, Bastiany Alexandra, Matteau Alexis, Mansour Samer, Gobeil François, Simion Oana-Maria, Kokis André, Bairey Merz C Noel, Potter Brian J
Impact of STEMI Diagnosis and Catheterization Laboratory Activation
Systems on Sex- and Age-Based Differences in Treatment Delay
CJC open,
2021; 3(6):
723-732.
Vogel Birgit, Acevedo Monica, Appelman Yolande, Bairey Merz C Noel, Chieffo Alaide, Figtree Gemma A, Guerrero Mayra, Kunadian Vijay, Lam Carolyn S P, Maas Angela H E M, Mihailidou Anastasia S, Olszanecka Agnieszka, Poole Jeanne E, Saldarriaga Clara, Saw Jacqueline, Zühlke Liesl, Mehran Roxana
The Lancet women and cardiovascular disease Commission: reducing the
global burden by 2030
Lancet (London, England),
2021; 397(10292):
2385-2438.
Wild Robert A, Hovey Kathleen M, Andrews Christopher, Robinson Jennifer G, Kaunitz Andrew M, Manson JoAnn E, Crandall Carolyn J, Paragallo Rachel, Shufelt Chrisandra, Merz C Noel Bairey
Cardiovascular disease (CVD) risk scores, age, or years since
menopause to predict cardiovascular disease in the Women's Health
Initiative
Menopause (New York, N.Y.),
2021; 28(6):
610-618.
Shimokawa Hiroaki, Suda Akira, Takahashi Jun, Berry Colin, Camici Paolo G, Crea Filippo, Escaned Javier, Ford Tom, Yii Eric, Kaski Juan Carlos, Kiyooka Takahiko, Mehta Puja K, Ong Peter, Ozaki Yukio, Pepine Carl, Rimoldi Ornella, Safdar Basmah, Sechtem Udo, Tsujita Kenichi, Yasuda Satoshi, Beltrame John F, Merz C Noel Bairey
Clinical characteristics and prognosis of patients with microvascular
angina: an international and prospective cohort study by the Coronary
Vasomotor Disorders International Study (COVADIS) Group
European heart journal,
2021; 333(10292):
35-39.
Samuel T Jake, Wei Janet, Sharif Behzad, Tamarappoo Balaji K, Pattisapu Varun, Maughan Jenna, Cipher Daisha J, Suppogu Nissi, Aldiwani Haider, Thomson Louise E J, Shufelt Chrisandra, Berman Daniel S, Li Debiao, Bairey Merz C Noel, Nelson Michael D
Diastolic dysfunction in women with ischemia and no obstructive
coronary artery disease: Mechanistic insight from magnetic resonance
imaging
International journal of cardiology,
2021; 331(10292):
1-7.
van den Hoogen Inge J, Gianni Umberto, Wood Malissa J, Taqueti Viviany R, Lin Fay Y, Hayes Sharonne N, Feuchtner Gudrun M, van Rosendael Alexander R, Wenger Nanette K, Wei Janet, Bairey Merz C Noel, Pepine Carl J, Shaw Leslee J, Shaw Leslee J
The Clinical Spectrum of Myocardial Infarction and Ischemia With
Nonobstructive Coronary Arteries in Women
JACC. Cardiovascular imaging,
2021; 14(5):
1053-1062.
Bello Natalie A, Bairey Merz C Noel, Brown Haywood, Davis Melinda B, Dickert Neal W, El Hajj Stephanie C, Giullian Cindy, Quesada Odayme, Park Ki, Sanghani Rupa M, Shaw Leslee, Volgman Annabelle Santos, Wenger Nanette K, Williams Dominique, Pepine Carl J, Lindley Kathryn J, Lindley Kathryn J
Diagnostic Cardiovascular Imaging and Therapeutic Strategies in
Pregnancy: JACC Focus Seminar 4/5
Journal of the American College of Cardiology,
2021; 77(14):
1813-1822.
Park Ki, Bairey Merz C Noel, Bello Natalie A, Davis Melinda, Duvernoy Claire, Elgendy Islam Y, Ferdinand Keith C, Hameed Afshan, Itchhaporia Dipti, Minissian Margo B, Reynolds Harmony, Mehta Puja, Russo Andrea M, Shah Rashmee U, Volgman Annabelle Santos, Wei Janet, Wenger Nanette K, Pepine Carl J, Lindley Kathryn J, Lindley Kathryn J
Management of Women With Acquired Cardiovascular Disease From
Pre-Conception Through Pregnancy and Postpartum: JACC Focus Seminar
3/5
Journal of the American College of Cardiology,
2021; 77(14):
1799-1812.
Lindley Kathryn J, Bairey Merz C Noel, Asgar Anita W, Bello Natalie A, Chandra Sonal, Davis Melinda B, Gomberg-Maitland Mardi, Gulati Martha, Hollier Lisa M, Krieger Eric V, Park Ki, Silversides Candice, Wolfe Natasha K, Pepine Carl J, Pepine Carl J
Management of Women With Congenital or Inherited Cardiovascular
Disease From Pre-Conception Through Pregnancy and Postpartum: JACC
Focus Seminar 2/5
Journal of the American College of Cardiology,
2021; 77(14):
1778-1798.
Tamarappoo Balaji, Samuel T Jake, Elboudwarej Omeed, Thomson Louise E J, Aldiwani Haider, Wei Janet, Mehta Puja, Cheng Susan, Sharif Behzad, AlBadri Ahmed, Handberg Eileen M, Petersen John, Pepine Carl J, Nelson Michael D, Bairey Merz C Noel
Left ventricular circumferential strain and coronary microvascular
dysfunction: A report from the Women's Ischemia Syndrome Evaluation
Coronary Vascular Dysfunction (WISE-CVD) Project
International journal of cardiology,
2021; 327(14):
25-30.
Barsky Lili, Shufelt Chrisandra, Lauzon Marie, Johnson B Delia, Berga Sarah L, Braunstein Glenn, Bittner Vera, Shaw Leslee, Reis Steven, Handberg Eileen, Pepine Carl J, Bairey Merz C Noel
Prior Oral Contraceptive Use and Longer Term Mortality Outcomes in
Women with Suspected Ischemic Heart Disease
Journal of women's health (2002),
2021; 30(3):
377-384.
Catov Janet M, McNeil Rebecca B, Marsh Derek J, Mercer Brian M, Bairey Merz C Noel, Parker Corette B, Pemberton Victoria L, Saade George R, Chen Yii-Der Ida, Chung Judith H, Ehrenthal Deborah B, Grobman William A, Haas David M, Parry Samuel, Polito LuAnn, Reddy Uma M, Silver Robert M, Simhan Hyagriv N, Wapner Ronald J, Kominiarek Michelle, Kreutz Rolf, Levine Lisa D, Greenland Philip, Greenland Philip
Early Pregnancy Atherogenic Profile in a First Pregnancy and
Hypertension Risk 2 to 7 Years After Delivery
Journal of the American Heart Association,
2021; 10(5):
e017216.
AlBadri Ahmed, Wei Janet, Quesada Odayme, Mehta Puja K, Xiao Yi, Ko Yi-An, Anderson R David, Petersen John, Azarbal Babak, Samuels Bruce, Henry Timothy D, Cook-Wiens Galen, Handberg Eileen M, Van Eyk Jennifer, Pepine Carl J, Bairey Merz C Noel
Coronary Vascular Function and Cardiomyocyte Injury: A Report From the
WISE-CVD
Arteriosclerosis, thrombosis, and vascular biology,
2020; 40(12):
3015-3021.
Roy Rajasree, Aldiwani Haider, Darouian Navid, Sharma Shilpa, Torbati Tina, Wei Janet, Nelson Michael D, Shufelt Chrisandra, Minissian Margo B, Li Lian, Merz C Noel Bairey, Mehta Puja K
Ambulatory and silent myocardial ischemia in women with coronary
microvascular dysfunction: Results from the Cardiac Autonomic Nervous
System study (CANS)
International journal of cardiology,
2020; 316(10):
1-6.
Shufelt Chrisandra L, Kim Andy, Joung Sandy, Barsky Lili, Arnold Corey, Cheng Susan, Dhawan Shivani, Fuller Garth, Speier William, Lopez Mayra, Mastali Mitra, Mouapi Kelly, van den Broek Irene, Wei Janet, Spiegel Brennan, Van Eyk Jennifer E, Bairey-Merz C Noel
Biometric and Psychometric Remote Monitoring and Cardiovascular Risk
Biomarkers in Ischemic Heart Disease
Journal of the American Heart Association,
2020; 9(18):
e016023.
Marzilli Mario, Crea Filippo, Morrone Doralisa, Bonow Robert O, Brown David L, Camici Paolo G, Chilian William M, DeMaria Anthony, Guarini Giacinta, Huqi Alda, Merz C Noel Bairey, Pepine Carl, Scali Maria Chiara, Weintraub William S, Boden William E
Myocardial ischemia: From disease to syndrome
International journal of cardiology,
2020; 314(9):
32-35.
Ford Thomas J, Ong Peter, Sechtem Udo, Beltrame John, Camici Paolo G, Crea Filippo, Kaski Juan-Carlos, Bairey Merz C Noel, Pepine Carl J, Shimokawa Hiroaki, Berry Colin, Berry Colin
Assessment of Vascular Dysfunction in Patients Without Obstructive
Coronary Artery Disease: Why, How, and When
JACC. Cardiovascular interventions,
2020; 13(16):
1847-1864.
Ebinger Joseph E, Achamallah Natalie, Ji Hongwei, Claggett Brian L, Sun Nancy, Botting Patrick, Nguyen Trevor-Trung, Luong Eric, Kim Elizabeth H, Park Eunice, Liu Yunxian, Rosenberry Ryan, Matusov Yuri, Zhao Steven, Pedraza Isabel, Zaman Tanzira, Thompson Michael, Raedschelders Koen, Berg Anders H, Grein Jonathan D, Noble Paul W, Chugh Sumeet S, Bairey Merz C Noel, Marbán Eduardo, Van Eyk Jennifer E, Solomon Scott D, Albert Christine M, Chen Peter, Cheng Susan
Pre-existing traits associated with Covid-19 illness severity
PloS one,
2020; 15(7):
e0236240.
Reynolds Harmony R, Shaw Leslee J, Min James K, Spertus John A, Chaitman Bernard R, Berman Daniel S, Picard Michael H, Kwong Raymond Y, Bairey-Merz C Noel, Cyr Derek D, Lopes Renato D, Lopez-Sendon Jose Luis, Held Claes, Szwed Hanna, Senior Roxy, Gosselin Gilbert, Nair Rajesh Gopalan, Elghamaz Ahmed, Bockeria Olga, Chen Jiyan, Chernyavskiy Alexander M, Bhargava Balram, Newman Jonathan D, Hinic Sasa B, Jaroch Joanna, Hoye Angela, Berger Jeffrey, Boden William E, O'Brien Sean M, Maron David J, Hochman Judith S, Hochman Judith S
Association of Sex With Severity of Coronary Artery Disease, Ischemia,
and Symptom Burden in Patients With Moderate or Severe Ischemia:
Secondary Analysis of the ISCHEMIA Randomized Clinical Trial
JAMA cardiology,
2020; 5(7):
773-786.
Quesada Odayme, Hermel Melody, Suppogu Nissi, Aldiwani Haider, Shufelt Chrisandra, Mehta Puja K, Cook-Wiens Galen, Maughan Jenna, Berman Daniel S, Thomson Louise E J, Handberg Eileen M, Pepine Carl J, Bairey Merz C Noel, Wei Janet
Temporal Trends in Angina, Myocardial Perfusion, and Left Ventricular
Remodeling in Women With No Obstructive Coronary Artery Disease Over
1-Year Follow-Up: Results From WISE-CVD
Journal of the American Heart Association,
2020; 9(13):
e016305.
Monk Catherine, Webster Rachel S, McNeil Rebecca B, Parker Corette B, Catov Janet M, Greenland Philip, Bairey Merz C Noel, Silver Robert M, Simhan Hyagriv N, Ehrenthal Deborah B, Chung Judith H, Haas David M, Mercer Brian M, Parry Samuel, Polito LuAnn, Reddy Uma M, Saade George R, Grobman William A, Grobman William A
Associations of perceived prenatal stress and adverse pregnancy
outcomes with perceived stress years after delivery
Archives of women's mental health,
2020; 23(3):
361-369.
Jones Erika, Wei Janet, Nelson Michael D, Bakir May, Mehta Puja K, Shufelt Chrisandra, Minissian Margo, Sharif Behzad, Pepine Carl J, Handberg Eileen, Cook-Wiens Galen, Sopko George, Bairey Merz C Noel
N-Terminal pro-B-type natriuretic peptide and coronary microvascular
dysfunction in women with preserved ejection fraction: A report from
the Women's Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction
(WISE-CVD) study
PloS one,
2020; 15(12):
e0243213.
Suppogu Nissi, Wei Janet, Nelson Michael D, Cook-Wiens Galen, Cheng Susan, Shufelt Chrisandra L, Thomson Louise E J, Tamarappoo Balaji, Berman Daniel S, Samuels Bruce, Azarbal Babak, Anderson R David, Petersen John W, Handberg Eileen M, Pepine Carl J, Merz C Noel Bairey
Resting coronary velocity and myocardial performance in women with
impaired coronary flow reserve: Results from the Women's Ischemia
Syndrome Evaluation-Coronary Vascular Dysfunction (WISE-CVD) study
International journal of cardiology,
2020; 309(8):
19-22.
Raad Mohamad, AlBadri Ahmed, Wei Janet, Mehta Puja K, Maughan Jenna, Gadh Adit, Thomson Louise, Jones Dean P, Quyyumi Arshed A, Pepine Carl J, Bairey Merz C Noel
Oxidative Stress Is Associated With Diastolic Dysfunction in Women
With Ischemia With No Obstructive Coronary Artery Disease
Journal of the American Heart Association,
2020; 9(10):
e015602.
Sedlak Tara, Herscovici Romana, Cook-Wiens Galen, Handberg Eileen, Wei Janet, Shufelt Chrisandra, Bittner Vera, Reis Steven E, Reichek Nathaniel, Pepine Carl, Bairey Merz C Noel
Predicted Versus Observed Major Adverse Cardiac Event Risk in Women
With Evidence of Ischemia and No Obstructive Coronary Artery Disease:
A Report From WISE (Women's Ischemia Syndrome Evaluation)
Journal of the American Heart Association,
2020; 9(7):
e013234.
Aldiwani Haider, Zaya Melody, Suppogu Nissi, Quesada Odayme, Johnson B Delia, Mehta Puja K, Shufelt Chrisandra, Petersen John, Azarbal Babak, Samuels Bruce, Anderson R David, Shaw Leslee J, Kar Saibal, Handberg Eileen, Kelsey Sheryl F, Pepine Carl J, Bairey Merz C Noel
Angina Hospitalization Rates in Women With Signs and Symptoms of
Ischemia But no Obstructive Coronary Artery Disease: A Report from the
WISE (Women's Ischemia Syndrome Evaluation) Study
Journal of the American Heart Association,
2020; 9(4):
e013168.
Quesada Odayme, AlBadri Ahmed, Wei Janet, Shufelt Chrisandra, Mehta Puja K, Maughan Jenna, Suppogu Nissi, Aldiwani Haider, Cook-Wiens Galen, Nelson Michael D, Sharif Behzad, Handberg Eileen M, Anderson R David, Petersen John, Berman Daniel S, Thomson Louise E J, Pepine Carl J, Merz C Noel Bairey
Design, methodology and baseline characteristics of the Women's
Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction (WISE-CVD)
American heart journal,
2020; 220(4):
224-236.