Robert H. Schiestl, Ph.D.


Work Titles
UCLA Professor, Pathology and Laboratory Medicine Professor, Radiation Oncology Professor, Environmental Health Sciences Faculty, Cellular and Molecular Pathology PhD Program
Education:
Degrees:
Ph.D., University of Vienna
B.S., University of Vienna

Contact Information:

Work Email Address:

rschiestl@mednet.ucla.edu


Website:

Pubmed Publications

Fax Number:

310.267.2578

Work Phone Number:

310.267.2087

310.267.2591

Work Address:

Office
CHS, 650 Charles E. Young Drive South
Los Angeles, CA 90095

71-295 CHS
Campus - 173216
CA

Laboratory
CHS, 650 Charles E. Young Drive South
Los Angeles, CA 90095


Detailed Biography:

Dr. Schiestl received his Ph.D. in Biology and Genetics from the University of Vienna, Austria, in 1983. He is currently a Professor of Pathology, Environmental Health and Radiation Oncology. Previously, he served as Assistant and Associate Professor in the Department of Cancer Cell Biology at the Harvard School of Public Health. He is Director of the UCLA Center for Environmental Genomics and a current member of the UCLA Cancer Center, UCLA Center of Occupational and Environmental Health, UCLA Interdepartmental Program in Molecular Toxicology (Faculty Advisory Committee), and UCLA ACCESS Graduate Program steering committee. He is also a member of the Planning Committee for the Environmental Mutagen Society meeting as well as Chair and Speak at the Symposium on "Genetic Instability" which will be held on March 11-15, 2003 at Miami Beach, Florida.

Publications:

Yamamoto Mitsuko L, Chapman Aaron M, Schiestl Robert H   Effects of side-stream tobacco smoke and smoke extract on glutathione- and oxidative DNA damage repair-deficient mice and blood cells Mutation research, 2013; 73(14): .
Yamamoto Mitsuko L, Maier Irene, Dang Angeline Tilly, Berry David, Liu Jared, Ruegger Paul M, Yang Jiue-In, Soto Phillip A, Presley Laura L, Reliene Ramune, Westbrook Aya M, Wei Bo, Loy Alexander, Chang Christopher, Braun Jonathan, Borneman James, Schiestl Robert H   Intestinal bacteria modify lymphoma incidence and latency by affecting systemic inflammatory state, oxidative stress, and leukocyte genotoxicity Cancer research, 2013; 73(14): 4222-32.
Hacke Katrin, Szakmary Akos, Cuddihy Andrew R, Rozengurt Nora, Lemp Nathan A, Aubrecht Jiri, Lawson Gregory W, Rao Nagesh P, Crooks Gay M, Schiestl Robert H, Kasahara Noriyuki   Combined preconditioning and in vivo chemoselection with 6-thioguanine alone achieves highly efficient reconstitution of normal hematopoiesis with HPRT-deficient bone marrow Experimental hematology, 2012; 40(1): 3-13.e3.
Sobol Zhanna, Schiestl Robert H   Intracellular and extracellular factors influencing Cr(VI) and Cr(III) genotoxicity Environmental and molecular mutagenesis, 2012; 53(2): 94-100.
Westbrook Aya M, Wei Bo, Hacke Katrin, Xia Menghang, Braun Jonathan, Schiestl Robert H   The role of tumour necrosis factor-α and tumour necrosis factor receptor signalling in inflammation-associated systemic genotoxicity Mutagenesis, 2012; 27(1): 77-86.
Aubrecht Jiri, Goad Mary E P, Czopik Agnieszka K, Lerner Charles P, Johnson Kevin A, Simpson Elizabeth M, Schiestl Robert H   A high G418-resistant neo(R) transgenic mouse and mouse embryonic fibroblast (MEF) feeder layers for cytotoxicity and gene targeting in vivo and in vitro Drug and chemical toxicology, 2011; 34(4): 433-9.
Cabeza-Arvelaiz Yofre, Fleming Sheila M, Richter Franziska, Masliah Eliezer, Chesselet Marie-Francoise, Schiestl Robert H   Analysis of striatal transcriptome in mice overexpressing human wild-type alpha-synuclein supports synaptic dysfunction and suggests mechanisms of neuroprotection for striatal neurons Molecular neurodegeneration, 2011; 6(9): 83.
Chan Cecilia Y, Zhu Jie, Schiestl Robert H   Effect of rad50 mutation on illegitimate recombination in Saccharomyces cerevisiae Molecular genetics and genomics : MGG, 2011; 285(6): 471-84.
Yamamoto Mitsuko L, Hafer Kurt, Reliene Ramune, Fleming Sheila, Kelly Owen, Hacke Katrin, Schiestl Robert H   Effects of 1 GeV/nucleon ⁵⁶Fe particles on longevity, carcinogenesis and neuromotor ability in Atm-deficient mice Radiation research, 2011; 175(2): 231-9.
Kim Kwanghee, Damoiseaux Robert, Norris Andrew J, Rivina Leena, Bradley Kenneth, Jung Michael E, Gatti Richard A, Schiestl Robert H, McBride William H   High throughput screening of small molecule libraries for modifiers of radiation responses International journal of radiation biology, 2011; 87(8): 839-45.
Westbrook Aya M, Wei Bo, Braun Jonathan, Schiestl Robert H   Intestinal inflammation induces genotoxicity to extraintestinal tissues and cell types in mice International journal of cancer. Journal international du cancer, 2011; 129(8): 1815-25.
Lynch Anthony M, Sasaki Jennifer C, Elespuru Rosalie, Jacobson-Kram David, Thybaud Véronique, De Boeck Marlies, Aardema Marilyn J, Aubrecht Jiri, Benz R Daniel, Dertinger Stephen D, Douglas George R, White Paul A, Escobar Patricia A, Fornace Albert, Honma Masamitsu, Naven Russell T, Rusling James F, Schiestl Robert H, Walmsley Richard M, Yamamura Eiji, van Benthem Jan, Kim James H   New and emerging technologies for genetic toxicity testing Environmental and molecular mutagenesis, 2011; 52(3): 205-23.
Hafer Kurt, Rivina Leena, Schiestl Robert H   Cell cycle dependence of ionizing radiation-induced DNA deletions and antioxidant radioprotection in Saccharomyces cerevisiae Radiation research, 2010; 173(6): 802-8.
Yamamoto Mitsuko L, Hafer Kurt, Reliene Ramune, Fleming Sheila, Kelly Owen, Hacke Katrin, Schiestl Robert H   Effects of 1 GeV/nucleon (56)Fe Particles on Longevity, Carcinogenesis and Neuromotor Ability in Atm-Deficient Mice Radiation research, 2010; 174(6): .
Reliene Ramune, Yamamoto Mitsuko L, Rao P Nagesh, Schiestl Robert H   Genomic instability in mice is greater in Fanconi anemia caused by deficiency of Fancd2 than Fancg Cancer research, 2010; 70(23): 9703-10.
Westbrook Aya M, Szakmary Akos, Schiestl Robert H   Mechanisms of intestinal inflammation and development of associated cancers: lessons learned from mouse models Mutation research, 2010; 705(1): 40-59.
Walter Martin A, Hildebrandt Isabel J, Hacke Katrin, Kesner Adam L, Kelly Owen, Lawson Gregory W, Phelps Michael E, Czernin Johannes, Weber Wolfgang A, Schiestl Robert H   Small-animal PET/CT for monitoring the development and response to chemotherapy of thymic lymphoma in Trp53-/- mice Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2010; 51(8): 1285-92.
Friedl Anna A, Kiechle Markus, Maxeiner Horst G, Schiestl Robert H, Eckardt-Schupp Friederike   Ty1 integrase overexpression leads to integration of non-Ty1 DNA fragments into the genome of Saccharomyces cerevisiae Molecular genetics and genomics : MGG, 2010; 284(4): 231-42.
Hafer Kurt, Rivina Yelena, Schiestl Robert H   Yeast DEL assay detects protection against radiation-induced cytotoxicity and genotoxicity: adaptation of a microtiter plate version Radiation research, 2010; 174(6): 719-26.
Westbrook Aya M, Wei Bo, Braun Jonathan, Schiestl Robert H   Intestinal mucosal inflammation leads to systemic genotoxicity in mice Cancer research, 2009; 69(11): 4827-34.
Scuric Zorica, Chan Cecilia Y, Hafer Kurt, Schiestl Robert H   Ionizing radiation induces microhomology-mediated end joining in trans in yeast and mammalian cells Radiation research, 2009; 171(4): 454-63.
Westbrook Aya M, Wei Bo, Braun Jonathan, Schiestl Robert H   More damaging than we think: systemic effects of intestinal inflammation Cell cycle (Georgetown, Tex.), 2009; 8(16): 2482-3.
Reliene Ramune, Pollard Julianne M, Sobol Zhanna, Trouiller Benedicte, Gatti Richard A, Schiestl Robert H   N-acetyl cysteine protects against ionizing radiation-induced DNA damage but not against cell killing in yeast and mammals Mutation research, 2009; 665(1-2): 37-43.
Galli Alvaro, Hafer Kurt, Cervelli Tiziana, Schiestl Robert H   The pol3-t hyperrecombination phenotype and DNA damage-induced recombination in Saccharomyces cerevisiae is RAD50 dependent Journal of biomedicine & biotechnology, 2009; 2009(4): 312710.
Trouiller Benedicte, Reliene Ramune, Westbrook Aya, Solaimani Parrisa, Schiestl Robert H   Titanium dioxide nanoparticles induce DNA damage and genetic instability in vivo in mice Cancer research, 2009; 69(22): 8784-9.
Rodriguez Chester E, Sobol Zhanna, Schiestl Robert H   9,10-Phenanthrenequinone induces DNA deletions and forward mutations via oxidative mechanisms in the yeast Saccharomyces cerevisiae Toxicology in vitro : an international journal published in association with BIBRA, 2008; 22(2): 296-300.
Hafer Kurt, Schiestl Robert H   Biological aspects of dichlorofluorescein measurement of cellular reactive oxygen species Radiation research, 2008; 170(3): 408.
Reliene Ramune, Fleming Sheila M, Chesselet Marie-Françoise, Schiestl Robert H   Effects of antioxidants on cancer prevention and neuromotor performance in Atm deficient mice Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2008; 46(4): 1371-7.
Yamamoto Mitsuko L, Reliene Ramune, Oshima Junko, Schiestl Robert H   Effects of human Werner helicase on intrachromosomal homologous recombination mediated DNA deletions in mice Mutation research, 2008; 644(1-2): 11-6.
Reliene Ramune, Schiestl Robert H   Experimental antioxidant therapy in ataxia telangiectasia Clinical medicine. Oncology, 2008; 2(1-2): 431-6.
Sobol Zhanna, Cook Natalie M, Schiestl Robert H   HNO induces DNA deletions in the yeast S. cerevisiae Mutation research, 2008; 638(1-2): 83-9.
Chan Cecilia Y, Galli Alvaro, Schiestl Robert H   Pol3 is involved in nonhomologous end-joining in Saccharomyces cerevisiae DNA repair, 2008; 7(9): 1531-41.
Chen Xuqi, Watkins Rebecca, Delot Emmanuele, Reliene Ramune, Schiestl Robert H, Burgoyne Paul S, Arnold Arthur P   Sex difference in neural tube defects in p53-null mice is caused by differences in the complement of X not Y genes Developmental neurobiology, 2008; 68(2): 265-73.
Hafer Kurt, Iwamoto Keisuke S, Iwamoto Keisuke K, Scuric Zorica, Schiestl Robert H   Adaptive response to gamma radiation in mammalian cells proficient and deficient in components of nucleotide excision repair Radiation research, 2007; 168(2): 168-74.
Reliene Ramune, Schiestl Robert H   Antioxidants suppress lymphoma and increase longevity in Atm-deficient mice The Journal of nutrition, 2007; 137(1 Suppl): 229S-232S.
Hontzeas Nikos, Hafer Kurt, Schiestl Robert H   Development of a microtiter plate version of the yeast DEL assay amenable to high-throughput toxicity screening of chemical libraries Mutation research, 2007; 634(1-2): 228-34.
Ku Warren W, Aubrecht Jiri, Mauthe Robert J, Schiestl Robert H, Fornace Albert J   Genetic toxicity assessment: employing the best science for human safety evaluation Part VII: Why not start with a single test: a transformational alternative to genotoxicity hazard and risk assessment Toxicological sciences : an official journal of the Society of Toxicology, 2007; 99(1): 20-5.
Gietz R Daniel, Schiestl Robert H   High-efficiency yeast transformation using the LiAc/SS carrier DNA/PEG method Nature protocols, 2007; 2(1): 31-4.
Reliene Ramune, Bishop Alexander J R, Schiestl Robert H   Involvement of homologous recombination in carcinogenesis Advances in genetics, 2007; 58(2): 67-87.
Chan Cecilia Y, Kiechle Markus, Manivasakam Palaniyandi, Schiestl Robert H   Ionizing radiation and restriction enzymes induce microhomology-mediated illegitimate recombination in Saccharomyces cerevisiae Nucleic acids research, 2007; 35(15): 5051-9.
Gietz R Daniel, Schiestl Robert H   Large-scale high-efficiency yeast transformation using the LiAc/SS carrier DNA/PEG method Nature protocols, 2007; 2(1): 38-41.
Gietz R Daniel, Schiestl Robert H   Microtiter plate transformation using the LiAc/SS carrier DNA/PEG method Nature protocols, 2007; 2(1): 5-8.
Gietz R Daniel, Schiestl Robert H   Quick and easy yeast transformation using the LiAc/SS carrier DNA/PEG method Nature protocols, 2007; 2(1): 35-7.
Ku, W. W. Aubrecht, J. Mauthe, R. J. Schiestl, R. H. Fornace, A. J., Jr.   Why Not Start With a Single Test: A Transformational Alternative to Genotoxicity Hazard and Risk Assessment Toxicol Sci, 2007; .
Reliene Ramune, Schiestl Robert H   Antioxidant N-acetyl cysteine reduces incidence and multiplicity of lymphoma in Atm deficient mice DNA repair, 2006; 5(7): 852-9.
Kirpnick-Sobol Zhanna, Reliene Ramune, Schiestl Robert H   Carcinogenic Cr(VI) and the nutritional supplement Cr(III) induce DNA deletions in yeast and mice Cancer research, 2006; 66(7): 3480-4.
Reliene Ramune, Goad Marry E P, Schiestl Robert H   Developmental cell death in the liver and newborn lethality of Ku86 deficient mice suppressed by antioxidant N-acetyl-cysteine DNA repair, 2006; 5(11): 1392-7.
Sommers Christopher H, Schiestl Robert H   Effect of benzene and its closed ring metabolites on intrachromosomal recombination in Saccharomyces cerevisiae Mutation research, 2006; 593(1-2): 1-8.
Reliene Ramune, Schiestl Robert H   Glutathione depletion by buthionine sulfoximine induces DNA deletions in mice Carcinogenesis, 2006; 27(2): 240-4.
Ohnishi Ken, Scuric Zorica, Yau David, Schiestl Robert H, Okamoto Noritomo, Takahashi Akihisa, Ohnishi Takeo   Heat-induced phosphorylation of NBS1 in human skin fibroblast cells Journal of cellular biochemistry, 2006; 99(6): 1642-50.
Howlett Niall G, Scuric Zorica, D'Andrea Alan D, Schiestl Robert H   Impaired DNA double strand break repair in cells from Nijmegen breakage syndrome patients DNA repair, 2006; 5(2): 251-7.
Hafer Kurt, Scuric Zorica, Iwamoto Keisuke S, Schiestl Robert H   Point-source irradiation with eccentric rotation causes inhomogeneous dose distribution Radiation research, 2006; 165(5): 616-20.
Bishop, A. J. Kosaras, B. Hollander, M. C. Fornace, A., Jr. Sidman, R. L. Schiestl, R. H.   p21 controls patterning but not homologous recombination in RPE development DNA Repair (Amst), 2006; 5(1): 111-20.
Ohnishi Ken, Scuric Zorica, Schiestl Robert H, Okamoto Noritomo, Takahashi Akihisa, Ohnishi Takeo   siRNA targeting NBS1 or XIAP increases radiation sensitivity of human cancer cells independent of TP53 status Radiation research, 2006; 166(3): 454-62.
Reliene Ramune, Hlavacova Alexandra, Mahadevan Brinda, Baird William M, Schiestl Robert H   Diesel exhaust particles cause increased levels of DNA deletions after transplacental exposure in mice Mutation research, 2005; 570(2): 245-52.
Kirpnick Zhanna, Homiski Michael, Rubitski Elizabeth, Repnevskaya Marina, Howlett Niall, Aubrecht Jiri, Schiestl Robert H   Yeast DEL assay detects clastogens Mutation research, 2005; 582(1-2): 116-34.
Brennan Richard J, Schiestl Robert H   Detecting carcinogens with the yeast DEL assay Methods in molecular biology (Clifton, N.J.), 2004; 262(2): 111-24.
Secretan, M. B. Scuric, Z. Oshima, J. Bishop, A. J. Howlett, N. G. Yau, D. Schiestl, R. H.   Effect of Ku86 and DNA-PKcs deficiency on non-homologous end-joining and homologous recombination using a transient transfection assay Mutat Res, 2004; 554(1-2): 351-64.
Reliene Ramune, Fischer Elvira, Schiestl Robert H   Effect of N-acetyl cysteine on oxidative DNA damage and the frequency of DNA deletions in atm-deficient mice Cancer research, 2004; 64(15): 5148-53.
Reliene Ramune, Bishop Alexander J R, Aubrecht Jiri, Schiestl Robert H   In vivo DNA deletion assay to detect environmental and genetic predisposition to cancer Methods in molecular biology (Clifton, N.J.), 2004; 262(2): 125-39.
Rugo Rebecca E, Schiestl Robert H   Increases in oxidative stress in the progeny of X-irradiated cells Radiation research, 2004; 162(4): 416-25.
Reliene Ramune, Bishop Alexander J R, Li Gloria, Schiestl Robert H   Ku86 deficiency leads to reduced intrachromosomal homologous recombination in vivo in mice DNA repair, 2004; 3(2): 103-11.
Stone Helen B, Moulder John E, Coleman C Norman, Ang K Kian, Anscher Mitchell S, Barcellos-Hoff Mary Helen, Dynan William S, Fike John R, Grdina David J, Greenberger Joel S, Hauer-Jensen Martin, Hill Richard P, Kolesnick Richard N, Macvittie Thomas J, Marks Cheryl, McBride William H, Metting Noelle, Pellmar Terry, Purucker Mary, Robbins Mike E, Schiestl Robert H, Seed Thomas M, Tomaszewski Joseph E, Travis Elizabeth L, Wallner Paul E, Wolpert Mary, Zaharevitz Daniel   Models for evaluating agents intended for the prophylaxis, mitigation and treatment of radiation injuries. Report of an NCI Workshop, December 3-4, 2003 Radiation research, 2004; 162(6): 711-28.
Egorov Andrey I, Howlett Niall G, Schiestl Robert H   Mutagen X and chlorinated tap water are recombinagenic in yeast Mutation research, 2004; 563(2): 159-69.
Howlett Niall G, Schiestl Robert H   Nucleotide excision repair deficiency causes elevated levels of chromosome gain in Saccharomyces cerevisiae DNA repair, 2004; 3(2): 127-34.
Bishop Alexander J R, Hollander M Christine, Kosaras Bela, Sidman Richard L, Fornace Albert J, Schiestl Robert H   Atm-, p53-, and Gadd45a-deficient mice show an increased frequency of homologous recombination at different stages during development Cancer research, 2003; 63(17): 5335-43.
Galli Alvaro, Cervelli Tiziana, Schiestl Robert H   Characterization of the hyperrecombination phenotype of the pol3-t mutation of Saccharomyces cerevisiae Genetics, 2003; 164(1): 65-79.
Reliene Ramune, Schiestl Robert H   Mouse models for induced genetic instability at endogenous loci Oncogene, 2003; 22(45): 7000-10.
Bishop Alexander J R, Schiestl Robert H   Role of homologous recombination in carcinogenesis Experimental and molecular pathology, 2003; 74(2): 94-105.
Storer, R. D. French, J. E. Donehower, L. A. Gulezian, D. Mitsumori, K. Recio, L. Schiestl, R. H. Sistare, F. D. Tamaoki, N. Usui, T. van Steeg, H.   Transgenic tumor models for carcinogen identification: the heterozygous Trp53-deficient and RasH2 mouse lines Mutat Res, 2003; 540(2): 165-76.
Chen Lishan, Huang Shurong, Lee Lin, Davalos Albert, Schiestl Robert H, Campisi Judith, Oshima Junko   WRN, the protein deficient in Werner syndrome, plays a critical structural role in optimizing DNA repair Aging cell, 2003; 2(4): 191-9.
Wiesmüller Lisa, Ford James M., Schiestl Robert H.   DNA Damage, Repair, and Diseases Journal of biomedicine & biotechnology, 2002; 2(2): 45.
Vonarx Edward J, Howlett Niall G, Schiestl Robert H, Kunz Bernard A   Detection of Arabidopsis thaliana AtRAD1 cDNA variants and assessment of function by expression in a yeast rad1 mutant Gene, 2002; 296(1-2): 1-9.
Bishop Alexander J. R., Schiestl Robert H.   Homologous Recombination and Its Role in Carcinogenesis Journal of biomedicine & biotechnology, 2002; 2(2): 75-85.
Oshima Junko, Huang Shurong, Pae Chong, Campisi Judith, Schiestl Robert H   Lack of WRN results in extensive deletion at nonhomologous joining ends Cancer research, 2002; 62(2): 547-51.
Kiechle Markus, Manivasakam Palaniyandi, Eckardt-Schupp Friederike, Schiestl Robert H, Friedl Anna A   Promoter-trapping in Saccharomyces cerevisiae by radiation-assisted fragment insertion Nucleic acids research, 2002; 30(24): e136.
Bishop, A. J. Schiestl, R. H.   Homologous recombination as a mechanism of carcinogenesis Biochim Biophys Acta, 2001; 1471(3): M109-21.
Long, N. C. Suh, J. Morrow, J. D. Schiestl, R. H. Murthy, G. G. Brain, J. D. Frei, B.   Ozone causes lipid peroxidation but little antioxidant depletion in exercising and nonexercising hamsters J Appl Physiol, 2001; 91(4): 1694-700.
Manivasakam, P. Aubrecht, J. Sidhom, S. Schiestl, R. H.   Restriction enzymes increase efficiencies of illegitimate DNA integration but decrease homologous integration in mammalian cells Nucleic Acids Res, 2001; 29(23): 4826-33.
Bishop, A. J. Kosaras, B. Carls, N. Sidman, R. L. Schiestl, R. H.   Susceptibility of proliferating cells to benzo[a]pyrene-induced homologous recombination in mice Carcinogenesis, 2001; 22(4): 641-9.
Bishop, A. J. Barlow, C. Wynshaw-Boris, A. J. Schiestl, R. H.   Atm deficiency causes an increased frequency of intrachromosomal homologous recombination in mice Cancer Res, 2000; 60(2): 395-9.
Bishop, A. J. Kosaras, B. Sidman, R. L. Schiestl, R. H.   Benzo(a)pyrene and X-rays induce reversions of the pink-eyed unstable mutation in the retinal pigment epithelium of mice Mutat Res, 2000; 457(1-2): 31-40.
Kiechle, M. Friedl, A. A. Manivasakam, P. Eckardt-Schupp, F. Schiestl, R. H.   DNA integration by Ty integrase in yku70 mutant Saccharomyces cerevisiae cells Mol Cell Biol, 2000; 20(23): 8836-44.
Bishop, A. J. Schiestl, R. H.   Homologous recombination as a mechanism for genome rearrangements: environmental and genetic effects Hum Mol Genet, 2000; 9(16): 2427-334.
Davidson, J. F. Schiestl, R. H.   Mis-targeting of multiple gene disruption constructs containing hisG Curr Genet, 2000; 38(4): 188-90.
Galli, A. Schiestl, R. H.   Cell division transforms mutagenic lesions into deletion-recombinagenic lesions in yeast cells Mutat Res, 1999; 429(1): 13-26.
Carls, N. Schiestl, R. H.   Effect of ionizing radiation on transgenerational appearance of p(un) reversions in mice Carcinogenesis, 1999; 20(12): 2351-4.
Aubrecht, J. Secretan, M. B. Bishop, A. J. Schiestl, R. H.   Involvement of p53 in X-ray induced intrachromosomal recombination in mice Carcinogenesis, 1999; 20(12): 2229-36.
Jalili, T. Murthy, G. G. Schiestl, R. H.   Cigarette smoke induces DNA deletions in the mouse embryo Cancer Res, 1998; 58(12): 2633-8.
Bonatti, S. Simili, M. Galli, A. Bagnato, P. Pigullo, S. Schiestl, R. H. Abbondandolo, A.   Inhibition of the Mr 70,000 S6 kinase pathway by rapamycin results in chromosome malsegregation in yeast and mammalian cells Chromosoma, 1998; 107(6-7): 498-506.
Manivasakam, P. Schiestl, R. H.   Nonhomologous end joining during restriction enzyme-mediated DNA integration in Saccharomyces cerevisiae Mol Cell Biol, 1998; 18(3): 1736-45.
Galli, A. Schiestl, R. H.   Yeast strains to detect genomic deletions induced by carcinogens in cell-cycle arrested cells Biotherapy, 1998; 11(2-3): 129-33.
Brennan, R. J. Schiestl, R. H.   Aniline and its metabolites generate free radicals in yeast Mutagenesis, 1997; 12(4): 215-20.
Schiestl, R. H. Aubrecht, J. Khogali, F. Carls, N.   Carcinogens induce reversion of the mouse pink-eyed unstable mutation Proc Natl Acad Sci U S A, 1997; 94(9): 4576-81.
Brennan, R. J. Schiestl, R. H.   Diaminotoluenes induce intrachromosomal recombination and free radicals in Saccharomyces cerevisiae Mutat Res, 1997; 381(2): 251-8.
Aubrecht, J. Goad, M. E. Simpson, E. M. Schiestl, R. H.   Expression of hygR in transgenic mice causes resistance to toxic effects of hygromycin B in vivo J Pharmacol Exp Ther, 1997; 281(2): 992-7.
Schiestl, R. H. Aubrecht, J. Yap, W. Y. Kandikonda, S. Sidhom, S.   Polychlorinated biphenyls and 2,3,7,8-tetrachlorodibenzo-p-dioxin induce intrachromosomal recombination in vitro and in vivo Cancer Res, 1997; 57(19): 4378-83.
Aubrecht, J. Goad, M. E. Schiestl, R. H.   Tissue specific toxicities of the anticancer drug 6-thioguanine is dependent on the Hprt status in transgenic mice J Pharmacol Exp Ther, 1997; 282(2): 1102-8.
Brennan, R. J. Schiestl, R. H.   Cadmium is an inducer of oxidative stress in yeast Mutat Res, 1996; 356(2): 171-8.
Davidson, J. F. Whyte, B. Bissinger, P. H. Schiestl, R. H.   Oxidative stress is involved in heat-induced cell death in Saccharomyces cerevisiae Proc Natl Acad Sci U S A, 1996; 93(10): 5116-21.
Brennan, R. J. Kandikonda, S. Khrimian, A. P. DeMilo, A. B. Liquido, N. J. Schiestl, R. H.   Saturated and monofluoro analogs of the oriental fruit fly attractant methyl eugenol show reduced genotoxic activities in yeast Mutat Res, 1996; 369(3-4): 175-81.
Zhu, J. Schiestl, R. H.   Topoisomerase I involvement in illegitimate recombination in Saccharomyces cerevisiae Mol Cell Biol, 1996; 16(4): 1805-12.
Aubrecht, J. Rugo, R. Schiestl, R. H.   Carcinogens induce intrachromosomal recombination in human cells Carcinogenesis, 1995; 16(11): 2841-6.
Manivasakam, P. Weber, S. C. McElver, J. Schiestl, R. H.   Micro-homology mediated PCR targeting in Saccharomyces cerevisiae Nucleic Acids Res, 1995; 23(14): 2799-800.
Yap, W. Y. Schiestl, R. H.   Nature of abortive transformation in Saccharomyces cerevisiae Curr Genet, 1995; 28(6): 517-20.
Gietz, R. D. Schiestl, R. H. Willems, A. R. Woods, R. A.   Studies on the transformation of intact yeast cells by the LiAc/SS-DNA/PEG procedure Yeast, 1995; 11(4): 355-60.
Brennan, R. J. Swoboda, B. E. Schiestl, R. H.   Oxidative mutagens induce intrachromosomal recombination in yeast Mutat Res, 1994; 308(2): 159-67.
Schiestl, R. H. Khogali, F. Carls, N.   Reversion of the mouse pink-eyed unstable mutation induced by low doses of x-rays Science, 1994; 266(5190): 1573-6.
Manivasakam, P. Schiestl, R. H.   High efficiency transformation of Saccharomyces cerevisiae by electroporation Nucleic Acids Res, 1993; 21(18): 4414-5.
Schiestl, R. H.   Nonmutagenic carcinogens induce intrachromosomal recombination in dividing yeast cells Environ Health Perspect, 1993; 101 Suppl 5: 179-84.
Schiestl, R. H. Wintersberger, U.   DNA damage induced mating type switching in Saccharomyces cerevisiae Mutat Res, 1992; 284(1): 111-23.
Gietz, D. St Jean, A. Woods, R. A. Schiestl, R. H.   Improved method for high efficiency transformation of intact yeast cells Nucleic Acids Res, 1992; 20(6): 1425.
Schiestl, R. H. Petes, T. D.   Integration of DNA fragments by illegitimate recombination in Saccharomyces cerevisiae Proc Natl Acad Sci U S A, 1991; 88(17): 7585-9.
Schiestl, R. H. Reddy, J. K.   Effect of peroxisome proliferators on intrachromosomal and interchromosomal recombination in yeast Carcinogenesis, 1990; 11(1): 173-6.
Schiestl, R. H. Gietz, R. D. Hastings, P. J. Wintersberger, U.   Interchromosomal and intrachromosomal recombination in rad 18 mutants of Saccharomyces cerevisiae Mol Gen Genet, 1990; 222(1): 25-32.
Schiestl, R. H. Gietz, R. D. Mehta, R. D. Hastings, P. J.   Carcinogens induce intrachromosomal recombination in yeast Carcinogenesis, 1989; 10(8): 1445-55.
Schiestl, R. H. Gietz, R. D.   High efficiency transformation of intact yeast cells using single stranded nucleic acids as a carrier Curr Genet, 1989; 16(5-6): 339-46.
Schiestl, R. H.   Nonmutagenic carcinogens induce intrachromosomal recombination in yeast Nature, 1989; 337(6204): 285-8.
Schiestl, R. H. Chan, W. S. Gietz, R. D. Mehta, R. D. Hastings, P. J.   Safrole, eugenol and methyleugenol induce intrachromosomal recombination in yeast Mutat Res, 1989; 224(4): 427-36.
Schiestl, R. H. Igarashi, S. Hastings, P. J.   Analysis of the mechanism for reversion of a disrupted gene Genetics, 1988; 119(2): 237-47.
Schiestl, R. H. Prakash, S.   RAD1, an excision repair gene of Saccharomyces cerevisiae, is also involved in recombination Mol Cell Biol, 1988; 8(9): 3619-26.
Schiestl, R. Wintersberger, U.   X-ray enhances mating type switching in heterothallic strains of Saccharomyces cerevisiae Mol Gen Genet, 1982; 186(4): 512-7.

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