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Shaping the Future

Jim Boulter, Ph.D.

Contact Information:

Fax Number:

(310) 825-7067
(310) 825-7067

Work Phone Number:

(310) 206-6665
(310) 206-9080

Work Address:

Laboratory
MRL Building, Room 2557
Los Angeles, CA 90095
UNITED STATES
Office
MRL Building, Room 2774
Los Angeles, CA 90095
UNITED STATES

Email Address:

jboulter@ucla.edu

Professor, Psychiatry and Biobehavioral Sciences

Associate Professor, Hatos Center for Neuropharmacology


Detailed Biography:

Dr. Jim Boulter is a Professor in the Department of Psychiatry and Biobehavioral Sciences. He received his doctorate degree in molecular biology from the University of California (Santa Barbara) and obtained postdoctoral training in molecular neuroscience at Dartmouth Medical School, the University of Texas (Houston), the University of California (San Diego), and the Salk Institute for Biological Studies. On the faculty of UCLA since 1996, Dr. Boulter's laboratory uses strains of genetically engineered mice to study the underlying cause of human inherited partial epilepsy and to characterize brain circuits involved in nicotine-induced dependence, tolerance, and withdrawal behaviors among habitual tobacco users. Dr. Boulter is a member of the UCLA Molecular Biology Institute, the Brain Research Institute, and the Hatos Research Center for Neuropharmacology.

Publications:

Salas Ramiro, Sturm Renea, Boulter Jim, De Biasi Mariella   Nicotinic receptors in the habenulo-interpeduncular system are necessary for nicotine withdrawal in mice The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009; 29(10): 3014-8.
Taranda Julian, Maison Stéphane F, Ballestero Jimena A, Katz Eleonora, Savino Jessica, Vetter Douglas E, Boulter Jim, Liberman M Charles, Fuchs Paul A, Elgoyhen A Belén   A point mutation in the hair cell nicotinic cholinergic receptor prolongs cochlear inhibition and enhances noise protection PLoS biology, 2009; 7(1): e18.
Lipovsek Marcela, Plazas Paola, Savino Jessica, Klaassen Alwin, Boulter Jim, Elgoyhen Ana Belén, Katz Eleonora   Properties of mutated murine alpha4beta2 nicotinic receptors linked to partial epilepsy Neuroscience letters, 2008; 434(2): 165-9.
Vetter, D. E. Katz, E. Maison, S. F. Taranda, J. Turcan, S. Ballestero, J. Liberman, M. C. Elgoyhen, A. B. Boulter, J.   The alpha10 nicotinic acetylcholine receptor subunit is required for normal synaptic function and integrity of the olivocochlear system Proc Natl Acad Sci U S A, 2007; 104(51): 20594-9.
Vetter Douglas E, Katz Eleonora, Maison Stéphane F, Taranda Julián, Turcan Sevin, Ballestero Jimena, Liberman M Charles, Elgoyhen A Belén, Boulter Jim   The alpha10 nicotinic acetylcholine receptor subunit is required for normal synaptic function and integrity of the olivocochlear system Proceedings of the National Academy of Sciences of the United States of America, 2007; 104(51): 20594-9.
Nakauchi, S. Brennan, R. J. Boulter, J. Sumikawa, K.   Nicotine gates long-term potentiation in the hippocampal CA1 region via the activation of alpha2* nicotinic ACh receptors Eur J Neurosci, 2007; 25(9): 2666-81.
Nakauchi Sakura, Brennan Robert J, Boulter Jim, Sumikawa Katumi   Nicotine gates long-term potentiation in the hippocampal CA1 region via the activation of alpha2* nicotinic ACh receptors The European journal of neuroscience, 2007; 25(9): 2666-81.
Klaassen, A. Glykys, J. Maguire, J. Labarca, C. Mody, I. Boulter, J.   Seizures and enhanced cortical GABAergic inhibition in two mouse models of human autosomal dominant nocturnal frontal lobe epilepsy Proc Natl Acad Sci U S A, 2006; 103(50): 19152-7.
Klaassen Alwin, Glykys Joseph, Maguire Jamie, Labarca Cesar, Mody Istvan, Boulter Jim   Seizures and enhanced cortical GABAergic inhibition in two mouse models of human autosomal dominant nocturnal frontal lobe epilepsy Proceedings of the National Academy of Sciences of the United States of America, 2006; 103(50): 19152-7.
Ladi, E. Nichols, J. T. Ge, W. Miyamoto, A. Yao, C. Yang, L. T. Boulter, J. Sun, Y. E. Kintner, C. Weinmaster, G.   The divergent DSL ligand Dll3 does not activate Notch signaling but cell autonomously attenuates signaling induced by other DSL ligands J Cell Biol, 2005; 170(6): 983-92.
Ladi Ena, Nichols James T, Ge Weihong, Miyamoto Alison, Yao Christine, Yang Liang-Tung, Boulter Jim, Sun Yi E, Kintner Chris, Weinmaster Gerry   The divergent DSL ligand Dll3 does not activate Notch signaling but cell autonomously attenuates signaling induced by other DSL ligands The Journal of cell biology, 2005; 170(6): 983-92.
London, S. E. Boulter, J. Schlinger, B. A.   Cloning of the zebra finch androgen synthetic enzyme CYP17: a study of its neural expression throughout posthatch development J Comp Neurol, 2003; 467(4): 496-508.
Cui, C. Booker, T. K. Allen, R. S. Grady, S. R. Whiteaker, P. Marks, M. J. Salminen, O. Tritto, T. Butt, C. M. Allen, W. R. Stitzel, J. A. McIntosh, J. M. Boulter, J. Collins, A. C. Heinemann, S. F.   The beta3 nicotinic receptor subunit: a component of alpha-conotoxin MII-binding nicotinic acetylcholine receptors that modulate dopamine release and related behaviors J Neurosci, 2003; 23(35): 11045-53.
London Sarah E, Boulter Jim, Schlinger Barney A   Cloning of the zebra finch androgen synthetic enzyme CYP17: a study of its neural expression throughout posthatch development The Journal of comparative neurology, 2003; 467(4): 496-508.
Cui Changhai, Booker T K, Allen Roberta S, Grady Sharon R, Whiteaker Paul, Marks Michael J, Salminen Outi, Tritto Theresa, Butt Christopher M, Allen W R, Stitzel Jerry A, McIntosh J Michael, Boulter Jim, Collins Allan C, Heinemann Stephen F   The beta3 nicotinic receptor subunit: a component of alpha-conotoxin MII-binding nicotinic acetylcholine receptors that modulate dopamine release and related behaviors The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003; 23(35): 11045-53.
Lioudyno, M. I. Verbitsky, M. Glowatzki, E. Holt, J. C. Boulter, J. Zadina, J. E. Elgoyhen, A. B. Guth, P. S.   The alpha9/alpha10-containing nicotinic ACh receptor is directly modulated by opioid peptides, endomorphin-1, and dynorphin B, proposed efferent cotransmitters in the inner ear Mol Cell Neurosci, 2002; 20(4): 695-711.
Haritunians Talin, Boulter Jim, Hicks Carol, Buhrman Jonathon, DiSibio Guy, Shawber Carrie, Weinmaster Gerry, Nofziger Donna, Schanen Carolyn   CADASIL Notch3 mutant proteins localize to the cell surface and bind ligand Circulation research, 2002; 90(5): 506-8.
Elgoyhen, A. B., Katz, E., Vetter, D. E., Rothlin, C. V., Heinemann, S., and Boulter, J   Alpha 10: A determinant of nicotinic cholinergic receptor function in mammalian vestibular and cochlear mechanosensory hair cells, PNAS, 2001; 98: 3501-3506.
Labarca, C Schwarz, J Deshpande, P Schwarz, S Nowak, MW Fonck, C Nashmi, R Kofuji, P Dang, H Shi, W Fidan, M Khakh, BS Chen, Z Bowers, BJ Boulter, J Wehner, JM Lester, HA   Point mutant mice with hypersensitive alpha 4 nicotinic receptors show dopaminergic deficits and increased anxiety Proceedings of the National Academy of Sciences of the United States of America. , 2001; 98(5): 2786-91.
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