Publications:
A selected list of publications:
Kepe Vladimir, Moghbel Mateen C, Långström Bengt, Zaidi Habib, Vinters Harry V, Huang Sung-Cheng, Satyamurthy Nagichettiar, Doudet Doris, Mishani Eyal, Cohen Robert M, Høilund-Carlsen Poul F, Alavi Abass, Barrio Jorge R
Amyloid-β Positron Emission Tomography Imaging Probes: A Critical
Review
Journal of Alzheimer's disease : JAD,
2013; 36(4):
613-31.
Smid Lojze M, Kepe Vladimir, Vinters Harry V, Bresjanac Mara, Toyokuni Tatsushi, Satyamurthy Nagichettiar, Wong Koon-Pong, Huang Sung-Cheng, Silverman Daniel H S, Miller Karen, Small Gary W, Barrio Jorge R
Postmortem 3-D brain hemisphere cortical tau and amyloid-β pathology
mapping and quantification as a validation method of neuropathology
imaging
Journal of Alzheimer's disease : JAD,
2013; 36(2):
261-74.
Yu Amy S, Hirayama Bruce A, Timbol Gerald, Liu Jie, Diez-Sampedro Ana, Kepe Vladimir, Satyamurthy Nagichettiar, Huang Sung-Cheng, Wright Ernest M, Barrio Jorge R
Regional distribution of SGLT activity in rat brain in vivo
American journal of physiology. Cell physiology,
2013; 304(3):
C240-7.
Schwarzenberg Johannes, Czernin Johannes, Cloughesy Timothy F, Ellingson Benjamin M, Pope Whitney B, Geist Cheri, Dahlbom Magnus, Silverman Daniel H S, Satyamurthy Nagichettiar, Phelps Michael E, Chen Wei
3'-deoxy-3'-18F-fluorothymidine PET and MRI for early survival
predictions in patients with recurrent malignant glioma treated with
bevacizumab
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
2012; 53(1):
29-36.
Petric Andrej, Johnson Scott A, Pham Hung V, Li Ying, Ceh Simon, Golobic Amalija, Agdeppa Eric D, Timbol Gerald, Liu Jie, Keum Gyochang, Satyamurthy Nagichettiar, Kepe Vladimir, Houk Kendall N, Barrio Jorge R
Dicyanovinylnaphthalenes for neuroimaging of amyloids and
relationships of electronic structures and geometries to binding
affinities
Proceedings of the National Academy of Sciences of the United States of America,
2012; 109(41):
16492-7.
Walter Franziska, Cloughesy Timothy, Walter Martin A, Lai Albert, Nghiemphu Phioanh, Wagle Naveed, Fueger Barbara, Satyamurthy Nagichettiar, Phelps Michael E, Czernin Johannes
Impact of 3,4-dihydroxy-6-18F-fluoro-L-phenylalanine PET/CT on
managing patients with brain tumors: the referring physician's
perspective
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
2012; 53(3):
393-8.
Keng Pei Yuin, Chen Supin, Ding Huijiang, Sadeghi Saman, Shah Gaurav J, Dooraghi Alex, Phelps Michael E, Satyamurthy Nagichettiar, Chatziioannou Arion F, Kim Chang-Jin, van Dam R Michael
Micro-chemical synthesis of molecular probes on an electronic
microfluidic device
Proceedings of the National Academy of Sciences of the United States of America,
2012; 109(3):
690-5.
Campbell Dean O, Yaghoubi Shahriar S, Su Ying, Lee Jason T, Auerbach Martin S, Herschman Harvey, Satyamurthy Nagichettiar, Czernin Johannes, Lavie Arnon, Radu Caius G
Structure-guided Engineering of Human Thymidine Kinase 2 as a Positron Emission Tomography Reporter Gene for Enhanced Phosphorylation of Non-natural Thymidine Analog Reporter Probe
The Journal of biological chemistry,
2012; 287(1):
446-54.
Schwarzenberg Johannes, Radu Caius G, Benz Matthias, Fueger Barbara, Tran Andrew Q, Phelps Michael E, Witte Owen N, Satyamurthy Nagichettiar, Czernin Johannes, Schiepers Christiaan
Human biodistribution and radiation dosimetry of novel PET probes
targeting the deoxyribonucleoside salvage pathway
European journal of nuclear medicine and molecular imaging,
2011; 38(4):
711-21.
Pouliot Frédéric, Karanikolas Breanne D W, Johnson Mai, Sato Makoto, Priceman Saul J, Stout David, Sohn Joanne, Satyamurthy Nagichettiar, deKernion Jean B, Wu Lily
In vivo imaging of intraprostatic-specific gene transcription by PET
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
2011; 52(5):
784-91.
Teng Edmond, Kepe Vladimir, Frautschy Sally A, Liu Jie, Satyamurthy Nagichettiar, Yang Fusheng, Chen Ping-Ping, Cole Graham B, Jones Mychica R, Huang Sung-Cheng, Flood Dorothy G, Trusko Stephen P, Small Gary W, Cole Gregory M, Barrio Jorge R
[F-18]FDDNP microPET imaging correlates with brain Aβ burden in a
transgenic rat model of Alzheimer disease: effects of aging, in vivo
blockade, and anti-Aβ antibody treatment
Neurobiology of disease,
2011; 43(3):
565-75.
Brewer Sarah, Nair-Gill Evan, Wei Bo, Chen Ling, Li Xiaoxiao, Riedinger Mireille, Campbell Dean O, Wiltzius Stephanie, Satyamurthy Nagichettiar, Phelps Michael E, Radu Caius, Witte Owen N, Braun Jonathan
Epithelial uptake of [18F]1-(2'-deoxy-2'-arabinofuranosyl) cytosine
indicates intestinal inflammation in mice
Gastroenterology,
2010; 138(4):
1266-75.
Yu Amy S, Hirayama Bruce A, Timbol Gerald, Liu Jie, Basarah Ernest, Kepe Vladimir, Satyamurthy Nagichettiar, Huang Sung-Cheng, Wright Ernest M, Barrio Jorge R
Functional expression of SGLTs in rat brain
American journal of physiology. Cell physiology,
2010; 299(6):
C1277-84.
Wardak Mirwais, Wong Koon-Pong, Shao Weber, Dahlbom Magnus, Kepe Vladimir, Satyamurthy Nagichettiar, Small Gary W, Barrio Jorge R, Huang Sung-Cheng
Movement correction method for human brain PET images: application to
quantitative analysis of dynamic 18F-FDDNP scans
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
2010; 51(2):
210-8.
Shu Chengyi J, Campbell Dean O, Lee Jason T, Tran Andrew Q, Wengrod Jordan C, Witte Owen N, Phelps Michael E, Satyamurthy Nagichettiar, Czernin Johannes, Radu Caius G
Novel PET probes specific for deoxycytidine kinase
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
2010; 51(7):
1092-8.
Kepe Vladimir, Ghetti Bernardino, Farlow Martin R, Bresjanac Mara, Miller Karen, Huang Sung-Cheng, Wong Koon-Pong, Murrell Jill R, Piccardo Pedro, Epperson Francine, Repovs Grega, Smid Lojze M, Petric Andrej, Siddarth Prabha, Liu Jie, Satyamurthy Nagichettiar, Small Gary W, Barrio Jorge R
PET of brain prion protein amyloid in Gerstmann-Sträussler-Scheinker
disease
Brain pathology (Zurich, Switzerland),
2010; 20(2):
419-30.
Braskie Meredith N, Klunder Andrea D, Hayashi Kiralee M, Protas Hillary, Kepe Vladimir, Miller Karen J, Huang S-C, Barrio Jorge R, Ercoli Linda M, Siddarth Prabha, Satyamurthy Nagichettiar, Liu Jie, Toga Arthur W, Bookheimer Susan Y, Small Gary W, Thompson Paul M
Plaque and tangle imaging and cognition in normal aging and
Alzheimer's disease
Neurobiology of aging,
2010; 31(10):
1669-78.
Wong Koon-Pong, Wardak Mirwais, Shao Weber, Dahlbom Magnus, Kepe Vladimir, Liu Jie, Satyamurthy Nagichettiar, Small Gary W, Barrio Jorge R, Huang Sung-Cheng
Quantitative analysis of [18F]FDDNP PET using subcortical white matter
as reference region
European journal of nuclear medicine and molecular imaging,
2010; 37(3):
575-88.
Toy Gerald, Austin Wayne R, Liao Hsiang-I, Cheng Donghui, Singh Arun, Campbell Dean O, Ishikawa Tomo-o, Lehmann Lynn W, Satyamurthy Nagichettiar, Phelps Michael E, Herschman Harvey R, Czernin Johannes, Witte Owen N, Radu Caius G
Requirement for deoxycytidine kinase in T and B lymphocyte
development
Proceedings of the National Academy of Sciences of the United States of America,
2010; 107(12):
5551-6.
Chen Wei, Delaloye Sibylle, Silverman Daniel H S, Geist Cheri, Czernin Johannes, Sayre James, Satyamurthy Nagichettiar, Pope Whitney, Lai Albert, Phelps Michael E, Cloughesy Timothy
Predicting treatment response of malignant gliomas to bevacizumab and
irinotecan by imaging proliferation with [18F] fluorothymidine
positron emission tomography: a pilot study
Journal of clinical oncology : official journal of the American Society of Clinical Oncology,
2007; 25(30):
4714-21.
Chen Wei, Silverman Daniel H S, Delaloye Sibylle, Czernin Johannes, Kamdar Nirav, Pope Whitney, Satyamurthy Nagichettiar, Schiepers Christiaan, Cloughesy Timothy
18F-FDOPA PET imaging of brain tumors: comparison study with 18F-FDG
PET and evaluation of diagnostic accuracy
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
2006; 47(6):
904-11.
Liu, Jie., Barrio, J. R., Satyamurthy, N.
Kinetics and mechanism of the defluorination of 8-fluoropurine nucleosides in basic and acidic media,
Journal of fluorine Chemistry,
2006; 127:
1175-1187.
Kepe Vladimir, Barrio Jorge R, Huang Sung-Cheng, Ercoli Linda, Siddarth Prabha, Shoghi-Jadid Kooresh, Cole Gregory M, Satyamurthy Nagichettiar, Cummings Jeffrey L, Small Gary W, Phelps Michael E
Serotonin 1A receptors in the living brain of Alzheimer's disease
patients
Proceedings of the National Academy of Sciences of the United States of America,
2006; 103(3):
702-7.
Chen Wei, Cloughesy Timothy, Kamdar Nirav, Satyamurthy Nagichettiar, Bergsneider Marvin, Liau Linda, Mischel Paul, Czernin Johannes, Phelps Michael E, Silverman Daniel H S
Imaging proliferation in brain tumors with 18F-FLT PET: comparison
with 18F-FDG
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
2005; 46(6):
945-52.
Waldherr Christian, Mellinghoff Ingo K, Tran Chris, Halpern Benjamin S, Rozengurt Nora, Safaei Arash, Weber Wolfgang A, Stout David, Satyamurthy Nagichettiar, Barrio Jorge, Phelps Michael E, Silverman Daniel H, Sawyers Charles L, Czernin Johannes
Monitoring antiproliferative responses to kinase inhibitor therapy in
mice with 3'-deoxy-3'-18F-fluorothymidine PET
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
2005; 46(1):
114-20.
Lee Chung-Cheng, Sui Guodong, Elizarov Arkadij, Shu Chengyi Jenny, Shin Young-Shik, Dooley Alek N, Huang Jiang, Daridon Antoine, Wyatt Paul, Stout David, Kolb Hartmuth C, Witte Owen N, Satyamurthy Nagichettiar, Heath James R, Phelps Michael E, Quake Stephen R, Tseng Hsian-Rong
Multistep synthesis of a radiolabeled imaging probe using integrated
microfluidics
Science (New York, N.Y.),
2005; 310(5755):
1793-6.
Peñuelas Iván, Mazzolini Guillermo, Boán José F, Sangro Bruno, MartÃ-Climent Josep, Ruiz MarÃa, Ruiz Juan, Satyamurthy Nagichettiar, Qian Cheng, Barrio Jorge R, Phelps Michael E, Richter José A, Gambhir Sanjiv S, Prieto Jesús
Positron emission tomography imaging of adenoviral-mediated transgene
expression in liver cancer patients
Gastroenterology,
2005; 128(7):
1787-95.
Toyokuni Tatsushi, Kumar J S Dileep, Walsh Joseph C, Shapiro Alan, Talley John J, Phelps Michael E, Herschman Harvey R, Barrio Jorge R, Satyamurthy Nagichettiar
Synthesis of
4-(5-[18F]fluoromethyl-3-phenylisoxazol-4-yl)benzenesulfonamide, a new
[18F]fluorinated analogue of valdecoxib, as a potential radiotracer
for imaging cyclooxygenase-2 with positron emission tomography
Bioorganic & medicinal chemistry letters,
2005; 15(21):
4699-702.
Green Leeta Alison, Nguyen Khoi, Berenji Bijan, Iyer Meera, Bauer Eileen, Barrio Jorge R, Namavari Mohammad, Satyamurthy Nagichettiar, Gambhir Sanjiv S
A tracer kinetic model for 18F-FHBG for quantitating herpes simplex
virus type 1 thymidine kinase reporter gene expression in living
animals using PET
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
2004; 45(9):
1560-70.
Toyokuni Tatsushi, Dileep Kumar J S, Gunawan Paula, Basarah Ernest S, Liu Jie, Barrio Jorge R, Satyamurthy Nagichettiar
Practical and reliable synthesis of
1,3,4,6-tetra-O-acetyl-2-O-trifluoromethanesulfonyl-beta-D-mannopyranose,
a precursor of 2-deoxy-2-[18F]fluoro-D-glucose (FDG)
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging,
2004; 6(5):
324-30.
Toyokuni, Tatsushi; Satyamurthy, Nagichettiar; Herschman, Harvey R.; Phelps, Michael E.; Barrio, Jorge R.
Cyclooxygenase-2 selective agents useful as imaging probes and related methods,
PCT Int. Appl,
2003;
60 pp. .
Inubushi Masayuki, Wu Joseph C, Gambhir Sanjiv S, Sundaresan Gobalakrishnan, Satyamurthy Nagichettiar, Namavari Mohammad, Yee Simon, Barrio Jorge R, Stout David, Chatziioannou Arion F, Wu Lily, Schelbert Heinrich R
Positron-emission tomography reporter gene expression imaging in rat
myocardium
Circulation,
2003; 107(2):
326-32.
Toyokuni, Tatsushi; Walsh, Joseph C.; Namavari, Mohammad; Shinde, Shirin S.; Moore, Jennifer R.; Barrio, Jorge R.; Satyamurthy, Nagichettiar.
Selective and Practical Synthesis of Penciclovir,
Synthetic Communications ,
2003; 33(22): :
3897-3905. .
Toyokuni, Tatsushi; Walsh, Joseph C.; Dominguez, Alan; Phelps, Michael E.; Barrio, Jorge R.; Gambhir, Sanjiv S.; Satyamurthy, Nagichettiar.
Synthesis of a New Heterobifunctional Linker, N-[4-(Aminooxy)butyl]maleimide, for Facile Access to a Thiol-Reactive 18F-Labeling Agent,
Bioconjugate Chemistry ,
2003; 14(6): :
1253-1259. .
Green Leeta A, Yap Cecelia S, Nguyen Khoi, Barrio Jorge R, Namavari Mohammad, Satyamurthy Nagichettiar, Phelps Michael E, Sandgren Eric P, Herschman Harvey R, Gambhir Sanjiv S
Indirect monitoring of endogenous gene expression by positron emission
tomography (PET) imaging of reporter gene expression in transgenic
mice
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging,
2002; 4(1):
71-81.
Shoghi-Jadid Kooresh, Small Gary W, Agdeppa Eric D, Kepe Vladimir, Ercoli Linda M, Siddarth Prabha, Read Stephen, Satyamurthy Nagichettiar, Petric Andrej, Huang Sung-Cheng, Barrio Jorge R
Localization of neurofibrillary tangles and beta-amyloid plaques in
the brains of living patients with Alzheimer disease
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry,
2002; 10(1):
24-35.
Liang Qianwa, Gotts Jeff, Satyamurthy Nagichettiar, Barrio Jorge, Phelps Michael E, Gambhir Sanjiv S, Herschman Harvey R
Noninvasive, repetitive, quantitative measurement of gene expression
from a bicistronic message by positron emission tomography, following
gene transfer with adenovirus
Molecular therapy : the journal of the American Society of Gene Therapy,
2002; 6(1):
73-82.
Satyamurthy N; Amarasekera Bernard; Alvord C William; Barrio Jorge R; Phelps Michael E Tantalum.
[18O]water target for the production of [18F]fluoride with high reactivity for the preparation of 2-deoxy-2-[18F]fluoro-D-glucose,
Molecular Imaging and Biology ,
2002; 4(1): :
65-70.
Bishop A, Satyamurthy N, Bida G, Phelps ME, Barrio JR
Identification and Quantitation of Gaseous Compounds of Fluorine Generated in [18F]F2 Target systems,
Nucl Med Biol ,
1996; 23:
391-405.
Bishop A, Satyamurthy N, Bida G, Phelps M, Barrio JR
Metals Suitable for Fluorine Gas Targets-First Use of Aluminum Body for the Production of [18F]F2,
Nuc Med Biol ,
1996; 23:
181-188.
Bishop A, Satyamurthy N, Bida G, Hendry G, Phelps ME, Barrio JR
Proton Irradiation of [18O]O2: Production of [18F]F2 and [18F]OF2-,
Nucl Med Biol ,
1996; 23:
189-200.
Lacan G, Satyamurthy N, Barrio JR
Fluorination of (E)-_-(Fluoromethylene)-m-Tyrosine: Regioselective Synthesis of 4-Fluoro-(E)-_-(Flurormethylene)-m-Tyrosine,
J Org Chem ,
1995; 60:
227-234.
Satyamurthy N, Namavari M, Barrio JR
18F Radiotracers for Medical Research. Chemtech 24(3): 25-32, 1994,
Chemtech ,
1994; 24(3):
25-32.
Namavari M, Satyamurthy N, Phelps ME, Barrio JR
Synthesis of 6-[18F] and 4-[18F]fluoro-L-m-tyrosines via regioselective radiofluorodestannylation,
Appl Radiat Isot ,
1993; 44:
527-536.
Namavari M, Bishop A, Satyamurthy N, Bida G, Barrio JR
Regioselective radiofluorodestannylation with [18F]F2 and [18F]CH3COOF: A high yield synthesis of 6-[18F]fluoro-L-dopa,
Appl Radiat Isot ,
1992; 43:
989-996.
Melega WP, Grafton ST, Huang SC, Satyamurthy N, Phelps ME, Barrio JR
6-[18F]Fluoro-L-DOPA metabolism in monkeys and humans: Biochemical parameters for the formulation of tracer kinetic models with positron emission tomography,
J Cereb Blood Flow Metab ,
1991; 11:
890-897.
Kleck JH, Benedict SH, Cook JS, Birdsall RL, Satyamurthy N
Assessment of 18F gaseous releases during the production of 18F-fluorodeoxyglucose,
Health Phys ,
1991; 60:
657-660.
Satyamurthy N, Barrio J.R.
Nucleophilic Fluorination of Aromatic Compounds,
US Patent, US 8,674,101 (2014),
;
.
Satyamurthy N, Barrio J.R.
No-Carrier-Added Nucleophilic [F-18]Fluorination of Aromatic Compounds,
US Patent, 8,742,139 (2014),
;
.
Liu J, Barrio JR, Satyamurthy N.
Efficient synthesis of 9-(4-[118F]fluoro-3-hydroxymethylbutyl)guanine ([18F] FHBG) and 9-[(3-[18F]fluoro-1-hydroxy-2-propoxy)methyl]guanine ([18F] FHPG),
J Fluorine Chem 201: 24 - 42 (2017),
;
.
Satyamurthy N, Liu J, Barrio JR.
Methods for Multi-dose Synthesis of [F-18]FDDNP for Clinical Settings. ,
US Patent 2018/0127355 A1 (2018),
;
.