Molecular Biology Influenza (Orthomyxo) and Sendai (Paramyxo) Viruses Major research effort in Dr. Nayak's lab is directed towards understanding the molecular basis of viral pathogenesis with special emphasis on pathogenesis, replication, assembly, morphogenesis and budding of influenza, Sendai and HIV viruses. Current projects involve defining (1) the function of different domains of influenza glycoproteins in polarized transport in epithelial cells; (2) the interaction among glycoproteins, the matrix protein and the viral RNP during assembly and budding; (3) functional basis of budding from the apical plasma membrane; (4) the steps involved in virus assembly at molecular level; (5) the role of matrix protein in budding and in viral pathogenesis; (6) the role of host proteins in virus budding.
See the MIMG web page and CV, , ; .
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