Daniel R. Scoles, Ph.D.


Work Titles
UCLA Assistant Professor, Medicine
Education:
Degrees:
Ph.D.

Contact Information:

Work Email Address:

daniel.scoles@cshs.org


Work Phone Number:

(310) 423-2159

Work Address:

Laboratory
Davis
Los Angeles, CA 90095

Office
Davis
Los Angeles, CA 90095


Publications:

A selected list of publications:

Scoles, D.R., Pavelka, J., Cass, I., Tran, H., Baldwin, R., Armstrong, K., and Karlan, B.Y.   Characterization of CSOC 882, a novel immortalized ovarian cancer cell line expressing EGFR, HER2, and activated AKT, Gynecologic Oncology, 2007; 104: 120-128.
Scoles, D.R., Das, A., and Pulst, S.M., (eds: Rimoin, D.L., Connor, J.M., Pyeritz, R.E., Korf, B.R.)   Primary Tumors of the Nervous System, Emory and Rimoin���s Principals and Practice of Medical Genetics, 2007; 5th Edition: .
Scoles, D.R., Yong, W., Qin, Y., Wawrowsky, K. and Pulst, S.M.   Schwannomin inhibits tumorigenesis through direct interaction with the eukaryotic initiation factor 3 subunit c (eIF3c), Human Molecular Genetics, 2006; 15: 1059-1070.
Scoles, D.R., Qin, Y., Nguyen, V., Gutmann, D.H., and Pulst   HRS inhibits EGF receptor signaling in the RT4 rat schwannoma cell line, Biochemical and Biophysical Research Communications, 2005; 335: 385-392.
Scoles, D.R. and Pulst, S.M. (eds: Aminoff, M., and Daroff, R.)   Brain Tumors, Genetics, Encyclopedia of the Neurological Sciences, 2003; 1: 470-472.
Oh, M.K., Scoles, D.R., Haipek, C., Gutmann, D.H., Pulst, S.M.   Genetic heterogeneity of stably transfected cell lines revealed by expression profiling with oligonucleotides microarrays, Journal of Cellular Biochemistry, 2003; 90: 1068-78.
Huynh, D.P., Scoles, D.R., Nguyen, D., and Pulst, S.M.   The autosomal recessive juvenile Parkinson disease gene product, parkin, interacts with and ubiquitinates synaptotagmin XI, Human Molecular Genetics, 2003; 12: 2587-97.
Scoles DR, Nguyen VD, Qin Y, Sun CX, Morrison H, Gutmann DH, Pulst SM   Neurofibromatosis 2 (NF2) tumor suppressor schwannomin and its interacting protein HRS regulate STAT signaling Human molecular genetics. , 2002; 11(25): 3179-89.
Sun CX, Haipek C, Scoles DR, Pulst SM, Giovannini M, Komada M and Gutmann DH   Functional analysis of the relationship between the neurofibromatosis 2 (NF2) tumor suppressor and its binding partner, hepatocyte growth factor-regulated tyrosine kinase substrate (HRS/HGS), Human Molecular Genetics, 2002; 11: 3167-3178.
Pulst, S.M. and Scoles, D.R. (eds: Rimoin, D.L., Connor, J.M., Pyeritz, R.E., Korf, B.R.)   Primary Tumors of the Nervous System, Emory and Rimoin’s Principals and Practice of Medical Genetics, 2002; 4th Edition(Chapter 121): 3231-3249.
Scoles DR, Chen M, Pulst SM   Effects of Nf2 missense mutations on schwannomin interactions Biochemical and biophysical research communications. , 2002; 290(1): 366-74.
Gutmann DH, Haipek CA, Burke SP, Sun CX, Scoles DR, Pulst SM   The NF2 interactor, hepatocyte growth factor-regulated tyrosine kinase substrate (HRS), associates with merlin in the "open" conformation and suppresses cell growth and motility Human molecular genetics. , 2001; 10(8): 825-34.
Huynh DP, Scoles DR, Ho TH, Del Bigio MR, Pulst SM   Parkin is associated with actin filaments in neuronal and nonneural cells Annals of neurology. , 2000; 48(5): 737-44.
Scoles DR, Huynh DP, Chen MS, Burke SP, Gutmann DH, Pulst SM   The neurofibromatosis 2 tumor suppressor protein interacts with hepatocyte growth factor-regulated tyrosine kinase substrate Human molecular genetics. , 2000; 9(11): 1567-74.
Scoles DR, Huynh DP, Morcos PA, Coulsell ER, Robinson NG, Tamanoi F, Pulst SM   Neurofibromatosis 2 tumour suppressor schwannomin interacts with betaII-spectrin Nature genetics. , 1998; 18(4): 354-9.
Scoles DR, Baser ME, Pulst SM   A missense mutation in the neurofibromatosis 2 gene occurs in patients with mild and severe phenotypes Neurology. , 1996; 47(2): 544-6.

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