Shen Hu, Ph.D.


Work Titles
CTSI Member, CTSI
UCLA Associate Professor, Dentistry Member, JCCC Signal Transduction and Therapeutics Program Area
Education:
Degrees:
Ph.D.

Contact Information:

Email Address:

shenhu@ucla.edu

Work Email Address:

shu@dentistry.ucla.edu


Detailed Biography:

Our group is studying head/neck cancer, pancreatic cancer and Sjogren's syndrome using proteomics and metabolomics, with a focus on understanding the molecular mechanisms of diseases and developing diagnostic/therapeutic applications. Using mass spectrometry and protein microarray technology, we have discovered target proteins involved in malignant transformation and tumor metastasis of head/neck and pancreatic cancers. We are interested in immunoproteasome in Sjogren's syndrome as well as single cell proteomics and related applications in stem cell and developmental biology.

Publications:

A selected list of publications:

Guo Mian, Shen Jia, Kwak Jin Hee, Choi Bogyu, Lee Min, Hu Shen, Zhang Xinli, Ting Kang, Soo Chia B, Chiu Robert H   Novel role for cyclophilin a in regulation of chondrogenic commitment and endochondral ossification Molecular and cellular biology, 2015; 35(12): 2119-30.
Cheng Xinquan, Liu Min, Zhang Anfeng, Hu Shen, Song Chunshan, Zhang Guoliang, Guo Xinwen   Size-controlled silver nanoparticles stabilized on thiol-functionalized MIL-53(Al) frameworks Nanoscale, 2015; 7(21): 9738-45.
Hu Shen, Wang Junhua, Ji Eoon Hye, Christison Terri, Lopez Linda, Huang Yingying   Targeted Metabolomic Analysis of Head and Neck Cancer Cells Using High Performance Ion Chromatography Coupled with a Q Exactive HF Mass Spectrometer Analytical chemistry, 2015; 35(12): .
Smedley Damian, Haider Syed, Durinck Steffen, Pandini Luca, Provero Paolo, Allen James, Arnaiz Olivier, Awedh Mohammad Hamza, Baldock Richard, Barbiera Giulia, Bardou Philippe, Beck Tim, Blake Andrew, Bonierbale Merideth, Brookes Anthony J, Bucci Gabriele, Buetti Iwan, Burge Sarah, Cabau Cédric, Carlson Joseph W, Chelala Claude, Chrysostomou Charalambos, Cittaro Davide, Collin Olivier, Cordova Raul, Cutts Rosalind J, Dassi Erik, Genova Alex Di, Djari Anis, Esposito Anthony, Estrella Heather, Eyras Eduardo, Fernandez-Banet Julio, Forbes Simon, Free Robert C, Fujisawa Takatomo, Gadaleta Emanuela, Garcia-Manteiga Jose M, Goodstein David, Gray Kristian, Guerra-Assunção José Afonso, Haggarty Bernard, Han Dong-Jin, Han Byung Woo, Harris Todd, Harshbarger Jayson, Hastings Robert K, Hayes Richard D, Hoede Claire, Hu Shen, Hu Zhi-Liang, Hutchins Lucie, Kan Zhengyan, Kawaji Hideya, Keliet Aminah, Kerhornou Arnaud, Kim Sunghoon, Kinsella Rhoda, Klopp Christophe, Kong Lei, Lawson Daniel, Lazarevic Dejan, Lee Ji-Hyun, Letellier Thomas, Li Chuan-Yun, Lio Pietro, Liu Chu-Jun, Luo Jie, Maass Alejandro, Mariette Jerome, Maurel Thomas, Merella Stefania, Mohamed Azza Mostafa, Moreews Francois, Nabihoudine Ibounyamine, Ndegwa Nelson, Noirot Céline, Perez-Llamas Cristian, Primig Michael, Quattrone Alessandro, Quesneville Hadi, Rambaldi Davide, Reecy James, Riba Michela, Rosanoff Steven, Saddiq Amna Ali, Salas Elisa, Sallou Olivier, Shepherd Rebecca, Simon Reinhard, Sperling Linda, Spooner William, Staines Daniel M, Steinbach Delphine, Stone Kevin, Stupka Elia, Teague Jon W, Dayem Ullah Abu Z, Wang Jun, Ware Doreen, Wong-Erasmus Marie, Youens-Clark Ken, Zadissa Amonida, Zhang Shi-Jian, Kasprzyk Arek   The BioMart community portal: an innovative alternative to large, centralized data repositories Nucleic acids research, 2015; 7(21): .
Chai Yang D, Zhang Lifeng, Yang Yan, Su Trent, Charugundla Prashant, Ai Jiye, Messadi Diana, Wong David T, Hu Shen   Discovery of potential serum protein biomarkers for lymph-node metastasis in oral cancer Head & neck, 2014; 7(21): .
He Guangwei, Zhao Jing, Hu Shen, Li Lingqiao, Li Zongyu, Li Yifan, Li Zhen, Wu Hong, Yang Xinlin, Jiang Zhongyi   Functionalized carbon nanotube via distillation precipitation polymerization and its application in nafion-based composite membranes ACS applied materials & interfaces, 2014; 6(17): 15291-301.
Yang Yan, Huang Junwei, Rabii Bahareh, Rabii Ramin, Hu Shen   Quantitative proteomic analysis of serum proteins from oral cancer patients: comparison of two analytical methods International journal of molecular sciences, 2014; 15(8): 14386-95.
Tian Tao, Wang Yi-Lu, Wang Ji-Zheng, Sun Kai, Zou Yu-Bao, Zhang Wei-Li, Zhu Ling, Shen Hu, Hui Ru-Tai, Zhou Xian-Liang, Song Lei   Myocardial bridging as a common phenotype of hypertrophic cardiomyopathy has no effect on prognosis The American journal of the medical sciences, 2014; 347(6): 429-33.
Cui Zhi-Qiang, Ling Zhi-Pei, Song Hui-Fang, Hu Shen, Sun Guo-Chen, Chen Xiao-Lei, Pan Long-Sheng, Li Chong, Xu Bai-Nan   Combining pyramidal tract mapping, microscopic-based neuronavigation, and intraoperative magnetic resonance imaging improves outcome of epilepsy foci resection in the sensorimotor cortex Turkish neurosurgery, 2014; 24(4): 538-45.
Wang Yilu, Wang Jizheng, Zou Yubao, Bao Jingru, Sun Kai, Zhu Ling, Tian Tao, Shen Hu, Zhou Xianliang, Ahmad Ferhaan, Hui Rutai, Song Lei   Female sex is associated with worse prognosis in patients with hypertrophic cardiomyopathy in China PloS one, 2014; 9(7): e102969.
Arellano-Garcia Martha E, Misuno Kaori, Tran Simon D, Hu Shen   Interferon-γ induces immunoproteasomes and the presentation of MHC I-associated peptides on human salivary gland cells PloS one, 2014; 9(8): e102878.
Wang Junhua, Christison Terri T, Misuno Kaori, Lopez Linda, Huhmer Andreas F, Huang Yingying, Hu Shen   Metabolomic profiling of anionic metabolites in head and neck cancer cells by capillary ion chromatography with Orbitrap mass spectrometry Analytical chemistry, 2014; 86(10): 5116-24.
Zhang Min, Chai Yang D, Brumbaugh Jeffrey, Liu Xiaojun, Rabii Ramin, Feng Sizhe, Misuno Kaori, Messadi Diana, Hu Shen   Oral cancer cells may rewire alternative metabolic pathways to survive from siRNA silencing of metabolic enzymes BMC cancer, 2014; 14(10): 223.
Misuno Kaori, Tran Simon D, Khalili Saeed, Huang Junwei, Liu Younan, Hu Shen   Quantitative analysis of protein and gene expression in salivary glands of Sjogren's-like disease NOD mice treated by bone marrow soup PloS one, 2014; 9(1): e87158.
Yan Yu-lan, Miao Rong-ming, Sun Ruo-han, Yao Yong-ming, Guo Ping, Hu Shen   [Epidemiological characteristics and trend of pneumoconiosis in Wuxi, China during 2006-2012] Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2013; 31(12): 912-6.
Liu Gang, Ma Hui-juan, Hu Pan-pan, Tian Yang-hua, Hu Shen, Fan Jin, Wang Kai   Effects of painful stimulation and acupuncture on attention networks in healthy subjects Behavioral and brain functions : BBF, 2013; 9(7): 23.
Li Jiang, Jia Bao Hui, Sun Jian, Lou Xiao Liang, Hu Shen Jiang   Phospholamban antisense RNA improves SR Ca2+-ATPase activity and left ventricular function in STZ-induced diabetic rats Biomedical and environmental sciences : BES, 2013; 26(7): 577-83.
Li Fang-Ye, Chen Xiao-Lei, Sai Xiao-Yong, Zhang Jia-Shu, Hu Shen, Li Jin-Jiang, Zheng Gang, Zhang Ting, Li Ye, Hou Meng-Zhuo, Xu Bai-Nan   [Application of intraoperative magnetic resonance imaging and multimodal navigation in surgical resection of glioblastoma] Zhonghua wai ke za zhi [Chinese journal of surgery], 2013; 51(6): 542-6.
Hu Shen, Wang Xiao-Chun, Yang Jin-Yan   [Interannual variation patterns of heavy metals concentrations in tree rings of Larix gmelinii near Xilin Lead-zinc Mine, Yichun of Northeast China] Ying yong sheng tai xue bao = The journal of applied ecology / Zhongguo sheng tai xue xue hui, Zhongguo ke xue yuan Shenyang ying yong sheng tai yan jiu suo zhu ban, 2013; 24(6): 1536-44.
Li Jinjiang, Chen Xiaolei, Zhang Jiashu, Zheng Gang, Lv Xueming, Li Fangye, Hu Shen, Zhang Ting, Xu Bainan   Intraoperative diffusion tensor imaging predicts the recovery of motor dysfunction after insular lesions Neural regeneration research, 2013; 8(15): 1400-9.
Tran Simon D, Liu Younan, Xia Dengsheng, Maria Ola M, Khalili Saeed, Wang Renee Wan-Jou, Quan Vu-Hung, Hu Shen, Seuntjens Jan   Paracrine effects of bone marrow soup restore organ function, regeneration, and repair in salivary glands damaged by irradiation PloS one, 2013; 8(4): e61632.
Li Fang-ye, Chen Xiao-lei, He Ting-ting, Zhang Jia-shu, Song Zhi-jun, Li Jin-jiang, Zheng Gang, Hu Shen, Zhang Ting, Xu Bai-nan   [Integration of metabolism images into multimodal neuronavigation for frameless stereotaxy] Zhonghua wai ke za zhi [Chinese journal of surgery], 2013; 51(4): 358-61.
Zheng Gang, Chen Xiaolei, Xu Bainan, Zhang Jiashu, Lv Xueming, Li Jinjiang, Li Fangye, Hu Shen, Zhang Ting, Li Ye   Plasticity of language pathways in patients with low-grade glioma: A diffusion tensor imaging study Neural regeneration research, 2013; 8(7): 647-54.
Tian Tao, Wang Yilu, Sun Kai, Wang Jizheng, Zou Yubao, Zhang Weili, Bao Jingru, Zhu Ling, Shen Hu, Hui Rutai, Zhou Xianliang, Song Lei   Clinical profile and prognostic significance of atrial fibrillation in hypertrophic cardiomyopathy Cardiology, 2013; 126(4): 258-64.
Misuno Kaori, Liu Xiaojun, Feng Sizhe, Hu Shen   Quantitative proteomic analysis of sphere-forming stem-like oral cancer cells Stem cell research & therapy, 2013; 4(6): 156.
Ren Hecheng, Chen Xiaolei, Sun Guochen, Hu Shen, Zheng Gang, Li Fangye, Li Jinjiang, Xu Bainan   Resection of subependymal giant cell astrocytoma guided by intraoperative magnetic resonance imaging and neuronavigation Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2013; 8(7): .
Zhang Bao, Guo Yi Kun, Li Shengbin, Zhang Liang Zhi, Lan Xian Yong, Hu Shen Rong, Chen Hong   Genotype and haplotype analysis of the AZGP1 gene in cattle Molecular biology reports, 2012; 39(12): 10475-9.
Yan Xinmin, Wang Qiuwei, Zhang Zhiqing, Xie Yiming, Zhang Hong, Razi Miriam, Hu Shen, Zhang Lijun, Cheng Jinluo, Pang Shen   Involvement of non-structural proteins (NS) in influenza A infection and viral tropism Biochemical and biophysical research communications, 2012; 428(1): 62-7.
Vissink Arjan, Bootsma Hendrika, Spijkervet Fred K L, Hu Shen, Wong David T, Kallenberg Cees G M   Current and future challenges in primary Sjögren's syndrome Current pharmaceutical biotechnology, 2012; 13(10): 2026-45.
Zhang Jia-shu, Chen Xiao-lei, Li Fang-ye, Li Jin-jiang, Zheng Gang, Zhang Ting, Hu Shen, Xu Bai-nan   [Influences of high-field intraoperative magnetic resonance imaging on the extent of resection in low-grade gliomas] Zhonghua yi xue za zhi, 2012; 92(25): 1738-41.
Zhang Jia-shu, Chen Xiao-lei, Li Fang-ye, Li Jin-jiang, Zheng Gang, Zhang Ting, Hu Shen, Xu Bai-nan   [Implementation of VarioGuide in stereotactic brain biopsy: a preliminary experience] Zhonghua yi xue za zhi, 2012; 92(21): 1468-71.
Zhang Jiashu, Chen Xiaolei, Zhao Yan, Li Fangye, Zheng Gang, Li Jinjiang, Zhang Ting, Hu Shen, Xu Bainan   [Reliability and accuracy of arcuate fasciculus navigation: analysis of 43 cases] Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2012; 32(5): 601-5.
Elashoff David, Zhou Hui, Reiss Jean, Wang Jianghua, Xiao Hua, Henson Bradley, Hu Shen, Arellano Martha, Sinha Uttam, Le Anh, Messadi Diana, Wang Marilene, Nabili Vishad, Lingen Mark, Morris Darly, Randolph Timothy, Feng Ziding, Akin David, Kastratovic Dragana A, Chia David, Abemayor Elliot, Wong David T W   Prevalidation of salivary biomarkers for oral cancer detection Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2012; 21(4): 664-72.
Hu Shen, Vissink Arjan, Arellano Martha, Roozendaal Caroline, Zhou Hui, Kallenberg Cees G M, Wong David T   Identification of autoantibody biomarkers for primary Sjögren's syndrome using protein microarrays Proteomics, 2011; 11(8): 1499-507.
Liu Yi, Wang Lina, Zhou Xuedong, Hu Shen, Zhang Siyu, Wu Hongkun   Effect of the antimicrobial decapeptide KSL on the growth of oral pathogens and Streptococcus mutans biofilm International journal of antimicrobial agents, 2011; 37(1): 33-8.
Liu Yi, Messadi Diana V, Wu Hongkun, Hu Shen   Oral lichen planus is a unique disease model for studying chronic inflammation and oral cancer Medical hypotheses, 2010; 75(6): 492-4.
Arellano-Garcia Martha E, Li Roger, Liu Xiaojun, Xie Yongming, Yan Xiaofei, Loo Joseph A, Hu Shen   Identification of tetranectin as a potential biomarker for metastatic oral cancer International journal of molecular sciences, 2010; 11(9): 3106-21.
Liu Xiaojun, Zhang Min, Go Vay Liang W, Hu Shen   Membrane proteomic analysis of pancreatic cancer cells Journal of biomedical science, 2010; 17(11): 74.
Hu Shen, Gao Kai, Pollard Rodney, Arellano-Garcia Martha, Zhou Hui, Zhang Lei, Elashoff David, Kallenberg Cees G M, Vissink Arjan, Wong David T   Preclinical validation of salivary biomarkers for primary Sjögren's syndrome Arthritis care & research, 2010; 62(11): 1633-8.
Hu Shen, Jiang Jiang, Wong David T   Proteomic analysis of saliva: 2D gel electrophoresis, LC-MS/MS, and Western blotting Methods in molecular biology (Clifton, N.J.), 2010; 666(9): 31-41.
Arellano Martha, Jiang Jiang, Zhou Xiaofeng, Zhang Lifeng, Ye Hui, Wong David T, Hu Shen   Current advances in identification of cancer biomarkers in saliva Frontiers in bioscience (Scholar edition), 2009; 1(6): 296-303.
Wei Fang, Patel Prabhudas, Liao Wei, Chaudhry Kishore, Zhang Lei, Arellano-Garcia Martha, Hu Shen, Elashoff David, Zhou Hui, Shukla Shilin, Shah Franky, Ho Chih-Ming, Wong David T   Electrochemical sensor for multiplex biomarkers detection Clinical cancer research : an official journal of the American Association for Cancer Research, 2009; 15(13): 4446-52.
Gao Kai, Zhou Hui, Zhang Lei, Lee Jin Wook, Zhou Qing, Hu Shen, Wolinsky Lawrence E, Farrell James, Eibl Guido, Wong David T   Systemic disease-induced salivary biomarker profiles in mouse models of melanoma and non-small cell lung cancer PloS one, 2009; 4(6): e5875.
Lehecka Martin, Dashti Reza, Romani Rossana, Celik Ozgür, Navratil Ondrej, Kivipelto Leena, Kivisaari Riku, Shen Hu, Ishii Keisuke, Karatas Ayse, Lehto Hanna, Kokuzawa Jouji, Niemelä Mika, Rinne Jaakko, Ronkainen Antti, Koivisto Timo, Jääskelainen Juha E, Hernesniemi Juha   Microneurosurgical management of internal carotid artery bifurcation aneurysms Surgical neurology, 2009; 71(6): 649-67.
Jiang Jiang, Park Noh Jin, Hu Shen, Wong David T   A universal pre-analytic solution for concurrent stabilization of salivary proteins, RNA and DNA at ambient temperature Archives of oral biology, 2009; 54(3): 268-73.
Hu Shen, Wong David T   Lectin microarray Proteomics. Clinical applications, 2009; 3(2): 148-154.
Yan Weihong, Apweiler Rolf, Balgley Brian M, Boontheung Pinmanee, Bundy Jonathan L, Cargile Benjamin J, Cole Steve, Fang Xueping, Gonzalez-Begne Mireya, Griffin Timothy J, Hagen Fred, Hu Shen, Wolinsky Lawrence E, Lee Cheng S, Malamud Daniel, Melvin James E, Menon Rajasree, Mueller Michael, Qiao Renli, Rhodus Nelson L, Sevinsky Joel R, States David, Stephenson James L, Than Shawn, Yates John R, Yu Weixia, Xie Hongwei, Xie Yongming, Omenn Gilbert S, Loo Joseph A, Wong David T   Systematic comparison of the human saliva and plasma proteomes Proteomics. Clinical applications, 2009; 3(1): 116-134.
Hu Shen, Zhou Michael, Jiang Jiang, Wang Jianghua, Elashoff David, Gorr Sven, Michie Sara A, Spijkervet Fred K L, Bootsma Hendrika, Kallenberg Cees G M, Vissink Arjan, Horvath Steve, Wong David T   Systems biology analysis of Sjögren's syndrome and mucosa-associated lymphoid tissue lymphoma in parotid glands Arthritis and rheumatism, 2009; 60(1): 81-92.
Kim Reuben H, Kim Roy, Chen Wei, Hu Shen, Shin Ki-Hyuk, Park No-Hee, Kang Mo K   Association of hsp90 to the hTERT promoter is necessary for hTERT expression in human oral cancer cells Carcinogenesis, 2008; 29(12): 2425-31.
Zhang Lin, Wu Yiling, Jia Zhenhua, Zhang Yun, Shen Hu Ying, Wang Xing Li   Protective effects of a compound herbal extract (Tong Xin Luo) on free fatty acid induced endothelial injury: implications of antioxidant system BMC complementary and alternative medicine, 2008; 8(19): 39.
Hu Shen, Arellano Martha, Boontheung Pinmanee, Wang Jianghua, Zhou Hui, Jiang Jiang, Elashoff David, Wei Roger, Loo Joseph A, Wong David T   Salivary proteomics for oral cancer biomarker discovery Clinical cancer research : an official journal of the American Association for Cancer Research, 2008; 14(19): 6246-52.
Ye Hui, Wang Anxun, Lee Bao-Shiang, Yu Tianwei, Sheng Shihu, Peng Tingsheng, Hu Shen, Crowe David L, Zhou Xiaofeng   Proteomic based identification of manganese superoxide dismutase 2 (SOD2) as a metastasis marker for oral squamous cell carcinoma Cancer genomics & proteomics, 2008; 5(2): 85-94.
Zhang Lifeng, Jiang Jiang, Arellano Martha, Zhang Lei, Yan Xinmin, Wong David T, Hu Shen   Quantification of Serum Proteins of Metastatic Oral Cancer Patients Using LC-MS/MS and iTRAQ Labeling The open proteomics journal, 2008; 1(2): 72-78.
Denny Paul, Hagen Fred K, Hardt Markus, Liao Lujian, Yan Weihong, Arellanno Martha, Bassilian Sara, Bedi Gurrinder S, Boontheung Pinmannee, Cociorva Daniel, Delahunty Claire M, Denny Trish, Dunsmore Jason, Faull Kym F, Gilligan Joyce, Gonzalez-Begne Mireya, Halgand Frédéric, Hall Steven C, Han Xuemei, Henson Bradley, Hewel Johannes, Hu Shen, Jeffrey Sherry, Jiang Jiang, Loo Joseph A, Ogorzalek Loo Rachel R, Malamud Daniel, Melvin James E, Miroshnychenko Olga, Navazesh Mahvash, Niles Richard, Park Sung Kyu, Prakobphol Akraporn, Ramachandran Prasanna, Richert Megan, Robinson Sarah, Sondej Melissa, Souda Puneet, Sullivan Mark A, Takashima Jona, Than Shawn, Wang Jianghua, Whitelegge Julian P, Witkowska H Ewa, Wolinsky Lawrence, Xie Yongming, Xu Tao, Yu Weixia, Ytterberg Jimmy, Wong David T, Yates John R, Fisher Susan J   The proteomes of human parotid and submandibular/sublingual gland salivas collected as the ductal secretions Journal of proteome research, 2008; 7(5): 1994-2006.
Hu Shen, Yen Yun, Ann David, Wong David T   Implications of salivary proteomics in drug discovery and development: a focus on cancer drug discovery Drug discovery today, 2007; 12(21-22): 911-6.
Hu Shen, Wang Jianghua, Meijer Jiska, Ieong Sonya, Xie Yongming, Yu Tianwei, Zhou Hui, Henry Sharon, Vissink Arjan, Pijpe Justin, Kallenberg Cees, Elashoff David, Loo Joseph A, Wong David T   Salivary proteomic and genomic biomarkers for primary Sjögren's syndrome Arthritis and rheumatism, 2007; 56(11): 3588-600.
Hu Shen, Wong David T   Oral cancer proteomics Current opinion in molecular therapeutics, 2007; 9(5): 467-76.
Hu Shen, Loo Joseph A, Wong David T   Human saliva proteome analysis and disease biomarker discovery Expert review of proteomics, 2007; 4(4): 531-8.
Dashti Reza, Hernesniemi Juha, Niemelä Mika, Rinne Jaakko, Lehecka Martin, Shen Hu, Lehto Hanna, Albayrak Baki S, Ronkainen Antti, Koivisto Timo, Jääskeläinen Juha E   Microneurosurgical management of distal middle cerebral artery aneurysms Surgical neurology, 2007; 67(6): 553-63.
Dashti Reza, Hernesniemi Juha, Niemelä Mika, Rinne Jaakko, Porras Matti, Lehecka Martin, Shen Hu, Albayrak Baki S, Lehto Hanna, Koroknay-Pál Päivi, de Oliveira Rafael Sillero, Perra Giancarlo, Ronkainen Antti, Koivisto Timo, Jääskeläinen Juha E   Microneurosurgical management of middle cerebral artery bifurcation aneurysms Surgical neurology, 2007; 67(5): 441-56.
Hu Shen, Yu Tianwei, Xie Yongming, Yang Yanan, Li Yang, Zhou Xiaofeng, Tsung Stephanie, Loo Rachel R, Loo Joseph R, Wong David T   Discovery of oral fluid biomarkers for human oral cancer by mass spectrometry Cancer genomics & proteomics, 2007; 4(2): 55-64.
Hu Shen, Loo Joseph A, Wong David T   Human saliva proteome analysis Annals of the New York Academy of Sciences, 2007; 1098(5): 323-9.
Dashti Reza, Rinne Jaakko, Hernesniemi Juha, Niemelä Mika, Kivipelto Leena, Lehecka Martin, Karatas Ayse, Avci Emel, Ishii Keisuke, Shen Hu, Peláez José G, Albayrak Baki S, Ronkainen Antti, Koivisto Timo, Jääskeläinen Juha E   Microneurosurgical management of proximal middle cerebral artery aneurysms Surgical neurology, 2007; 67(1): 6-14.
Hu Shen, Loo Joseph A, Wong David T   Human body fluid proteome analysis Proteomics, 2006; 6(23): 6326-53.
Randell Tarja, Niemelä Mika, Kyttä Juha, Tanskanen Päivi, Määttänen Markku, Karatas Ayse, Ishii Keisuke, Dashti Reza, Shen Hu, Hernesniemi Juha   Principles of neuroanesthesia in aneurysmal subarachnoid hemorrhage: The Helsinki experience Surgical neurology, 2006; 66(4): 382-8; discussion 388.
Hernesniemi Juha, Niemelä Mika, Dashti Reza, Karatas Ayse, Kivipelto Leena, Ishii Keisuke, Rinne Jaakko, Ronkainen Antti, Peláez José G, Koivisto Timo, Kivisaari Riku, Shen Hu, Lehecka Martin, Frösen Juhana, Piippo Anna, Avci Emel, Jääskeläinen Juha E   Principles of microneurosurgery for safe and fast surgery Surgical technology international, 2006; 15(1): 305-10.
Nagy Laszlo, Ishii Keisuke, Karatas Ayse, Shen Hu, Vajda Janos, Niemelä Mika, Jääskeläinen Juha, Hernesniemi Juha, Toth Szabolcs   Water dissection technique of Toth for opening neurosurgical cleavage planes Surgical neurology, 2006; 65(1): 38-41; discussion 41.
Hernesniemi Juha, Ishii Keisuke, Karatas Ayse, Kivipelto Leena, Niemelä Mika, Nagy Laszlo, Shen Hu   Surgical technique to retract the tentorial edge during subtemporal approach: technical note Neurosurgery, 2005; 57(4 Suppl): E408; discussion E408.
Hernesniemi Juha, Niemelä Mika, Karatas Ayse, Kivipelto Leena, Ishii Keisuke, Rinne Jaakko, Ronkainen Antti, Koivisto Timo, Kivisaari Riku, Shen Hu, Lehecka Martin, Frösen Juhana, Piippo Anna, Jääskeläinen Juha E   Some collected principles of microneurosurgery: simple and fast, while preserving normal anatomy: a review Surgical neurology, 2005; 64(3): 195-200.
Yeo Marie, Rha Sung Young, Jeung Hei Cheul, Hu Shen Xiong, Yang Sang Hwa, Kim Yang Seok, An Sung Whan, Chung Hyun Cheol   Attenuation of telomerase activity by hammerhead ribozyme targeting human telomerase RNA induces growth retardation and apoptosis in human breast tumor cells International journal of cancer. Journal international du cancer, 2005; 114(3): 484-9.
Hu Shen, Xie Yongming, Ramachandran Prasanna, Ogorzalek Loo Rachel R, Li Yang, Loo Joseph A, Wong David T   Large-scale identification of proteins in human salivary proteome by liquid chromatography/mass spectrometry and two-dimensional gel electrophoresis-mass spectrometry Proteomics, 2005; 5(6): 1714-28.
Hu Shen, Denny Patricia, Denny Paul, Xie Yongming, Loo Joseph A, Wolinsky Lawrence E, Li Yang, McBride Jim, Ogorzalek Loo Rachel R, Navazesh Mavash, Wong David T   Differentially expressed protein markers in human submandibular and sublingual secretions International journal of oncology, 2004; 25(5): 1423-30.
Michels David A, Hu Shen, Dambrowitz K Amy, Eggertson Michael J, Lauterbach Kevin, Dovichi Norman J   Capillary sieving electrophoresis-micellar electrokinetic chromatography fully automated two-dimensional capillary electrophoresis analysis of Deinococcus radiodurans protein homogenate Electrophoresis, 2004; 25(18-19): 3098-105.
Hu Shen, Michels David A, Fazal Md Abul, Ratisoontorn Chootima, Cunningham Michael L, Dovichi Norman J   Capillary sieving electrophoresis/micellar electrokinetic capillary chromatography for two-dimensional protein fingerprinting of single mammalian cells Analytical chemistry, 2004; 76(14): 4044-9.
Ye Mingliang, Hu Shen, Schoenherr Regine M, Dovichi Norman J   On-line protein digestion and peptide mapping by capillary electrophoresis with post-column labeling for laser-induced fluorescence detection Electrophoresis, 2004; 25(9): 1319-26.
Zhou Xiaofeng, Cole Steven W, Hu Shen, Wong David T W   Detection of DNA copy number abnormality by microarray expression analysis Human genetics, 2004; 114(5): 464-7.
Ye Mingliang, Hu Shen, Quigley Wes W C, Dovichi Norman J   Post-column fluorescence derivatization of proteins and peptides in capillary electrophoresis with a sheath flow reactor and 488 nm argon ion laser excitation Journal of chromatography. A, 2004; 1022(1-2): 201-6.
Dovichi Norman J, Hu Shen   Chemical cytometry Current opinion in chemical biology, 2003; 7(5): 603-8.
Hu Shen, Le Zhang, Krylov Sergey, Dovichi Norman J   Cell cycle-dependent protein fingerprint from a single cancer cell: image cytometry coupled with single-cell capillary sieving electrophoresis Analytical chemistry, 2003; 75(14): 3495-501.
Hu Shen, Le Zhang, Newitt Richard, Aebersold Ruedi, Kraly James R, Jones Megan, Dovichi Norman J   Identification of proteins in single-cell capillary electrophoresis fingerprints based on comigration with standard proteins Analytical chemistry, 2003; 75(14): 3502-5.
Zhang Le, Hu Shen, Cook Lillian, Dovichi Norman J   Analysis of aminophospholipid molecular species by methyl-beta-cyclodextrin modified micellar electrokinetic capillary chromatography with laser-induced fluorescence detection Electrophoresis, 2002; 23(17): 3071-7.
Hu Shen, Jiang Jiang, Cook Lillian M, Richards Dawn P, Horlick Laura, Wong Brandon, Dovichi Norman J   Capillary sodium dodecyl sulfate-DALT electrophoresis with laser-induced fluorescence detection for size-based analysis of proteins in human colon cancer cells Electrophoresis, 2002; 23(18): 3136-42.
Hu Shen, Dovichi Norman J   Capillary electrophoresis for the analysis of biopolymers Analytical chemistry, 2002; 74(12): 2833-50.
Michels David A, Hu Shen, Schoenherr Regine M, Eggertson Michael J, Dovichi Norman J   Fully automated two-dimensional capillary electrophoresis for high sensitivity protein analysis Molecular & cellular proteomics : MCP, 2002; 1(1): 69-74.

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