Publications:
A selected list of publications:
Cobos Enrique J, Nickerson Chelsea A, Gao Fuying, Chandran Vijayendran, Bravo-Caparrós Inmaculada, González-Cano Rafael, Riva Priscilla, Andrews Nick A, Latremoliere Alban, Seehus Corey R, Perazzoli Gloria, Nieto Francisco R, Joller Nicole, Painter Michio W, Ma Chi Him Eddie, Omura Takao, Chesler Elissa J, Geschwind Daniel H, Coppola Giovanni, Rangachari Manu, Woolf Clifford J, Costigan Michael
Mechanistic Differences in Neuropathic Pain Modalities Revealed by
Correlating Behavior with Global Expression Profiling
Cell reports,
2018; 22(5):
1301-1312.
Langfelder Peter, Gao Fuying, Wang Nan, Howland David, Kwak Seung, Vogt Thomas F, Aaronson Jeffrey S, Rosinski Jim, Coppola Giovanni, Horvath Steve, Yang X William
MicroRNA signatures of endogenous Huntingtin CAG repeat expansion in
mice
PloS one,
2018; 13(1):
e0190550.
Fontes Mariana M, Guvenek Aysegul, Kawaguchi Riki, Zheng Dinghai, Huang Alden, Ho Victoria M, Chen Patrick B, Liu Xiaochuan, O'Dell Thomas J, Coppola Giovanni, Tian Bin, Martin Kelsey C
Activity-Dependent Regulation of Alternative Cleavage and
Polyadenylation During Hippocampal Long-Term Potentiation
Scientific reports,
2017; 7(1):
17377.
Svardal Hannes, Jasinska Anna J, Apetrei Cristian, Coppola Giovanni, Huang Yu, Schmitt Christopher A, Jacquelin Beatrice, Ramensky Vasily, Müller-Trutwin Michaela, Antonio Martin, Weinstock George, Grobler J Paul, Dewar Ken, Wilson Richard K, Turner Trudy R, Warren Wesley C, Freimer Nelson B, Nordborg Magnus
Ancient hybridization and strong adaptation to viruses across African
vervet monkey populations
Nature genetics,
2017; 49(12):
1705-1713.
Perry David C, Brown Jesse A, Possin Katherine L, Datta Samir, Trujillo Andrew, Radke Anneliese, Karydas Anna, Kornak John, Sias Ana C, Rabinovici Gil D, Gorno-Tempini Maria Luisa, Boxer Adam L, De May Mary, Rankin Katherine P, Sturm Virginia E, Lee Suzee E, Matthews Brandy R, Kao Aimee W, Vossel Keith A, Tartaglia Maria Carmela, Miller Zachary A, Seo Sang Won, Sidhu Manu, Gaus Stephanie E, Nana Alissa L, Vargas Jose Norberto S, Hwang Ji-Hye L, Ossenkoppele Rik, Brown Alainna B, Huang Eric J, Coppola Giovanni, Rosen Howard J, Geschwind Daniel, Trojanowski John Q, Grinberg Lea T, Kramer Joel H, Miller Bruce L, Seeley William W
Clinicopathological correlations in behavioural variant frontotemporal
dementia
Brain : a journal of neurology,
2017; 140(12):
3329-3345.
Jasinska Anna J, Zelaya Ivette, Service Susan K, Peterson Christine B, Cantor Rita M, Choi Oi-Wa, DeYoung Joseph, Eskin Eleazar, Fairbanks Lynn A, Fears Scott, Furterer Allison E, Huang Yu S, Ramensky Vasily, Schmitt Christopher A, Svardal Hannes, Jorgensen Matthew J, Kaplan Jay R, Villar Diego, Aken Bronwen L, Flicek Paul, Nag Rishi, Wong Emily S, Blangero John, Dyer Thomas D, Bogomolov Marina, Benjamini Yoav, Weinstock George M, Dewar Ken, Sabatti Chiara, Wilson Richard K, Jentsch J David, Warren Wesley, Coppola Giovanni, Woods Roger P, Freimer Nelson B
Genetic variation and gene expression across multiple tissues and
developmental stages in a nonhuman primate
Nature genetics,
2017; 49(12):
1714-1721.
Lee Suzee E, Sias Ana C, Mandelli Maria Luisa, Brown Jesse A, Brown Alainna B, Khazenzon Anna M, Vidovszky Anna A, Zanto Theodore P, Karydas Anna M, Pribadi Mochtar, Dokuru Deepika, Coppola Giovanni, Geschwind Dan H, Rademakers Rosa, Gorno-Tempini Maria Luisa, Rosen Howard J, Miller Bruce L, Seeley William W
Network degeneration and dysfunction in presymptomatic C9ORF72
expansion carriers
NeuroImage. Clinical,
2017; 14(6):
286-297.
Laks Dan R, Oses-Prieto Juan A, Alvarado Alvaro G, Nakashima Jonathan, Chand Shreya, Azzam Daniel B, Gholkar Ankur A, Sperry Jantzen, Ludwig Kirsten, Condro Michael C, Nazarian Serli, Cardenas Anjelica, Shih Michelle Y S, Damoiseaux Robert, France Bryan, Orozco Nicholas, Visnyei Koppany, Crisman Thomas J, Gao Fuying, Torres Jorge Z, Coppola Giovanni, Burlingame Alma L, Kornblum Harley I
A Molecular Cascade Modulates MAP1B and Confers Resistance to mTOR
Inhibition in Human Glioblastoma
Neuro-oncology,
2017; 49(12):
1705-1713.
Olney Nicholas T, Alquezar Carolina, Ramos Eliana Marisa, Nana Alissa L, Fong Jamie C, Karydas Anna M, Taylor Joanne B, Stephens Melanie L, Argouarch Andrea R, Van Berlo Victoria A, Dokuru Deepika R, Sherr Elliott H, Jicha Gregory A, Dillon William P, Desikan Rahul S, De May Mary, Seeley William W, Coppola Giovanni, Miller Bruce L, Kao Aimee W
Linking tuberous sclerosis complex, excessive mTOR signaling, and
age-related neurodegeneration: a new association between TSC1 mutation
and frontotemporal dementia
Acta neuropathologica,
2017; 134(5):
813-816.
Watanabe Momoko, Buth Jessie E, Vishlaghi Neda, de la Torre-Ubieta Luis, Taxidis Jiannis, Khakh Baljit S, Coppola Giovanni, Pearson Caroline A, Yamauchi Ken, Gong Danyang, Dai Xinghong, Damoiseaux Robert, Aliyari Roghiyh, Liebscher Simone, Schenke-Layland Katja, Caneda Christine, Huang Eric J, Zhang Ye, Cheng Genhong, Geschwind Daniel H, Golshani Peyman, Sun Ren, Novitch Bennett G
Self-Organized Cerebral Organoids with Human-Specific Features Predict
Effective Drugs to Combat Zika Virus Infection
Cell reports,
2017; 21(2):
517-532.
Touma Marlin, Kang Xuedong, Gao Fuying, Zhao Yan, Cass Ashley A, Biniwale Reshma, Xiao Xinshu, Eghbali Mansuoreh, Coppola Giovanni, Reemtsen Brian, Wang Yibin
Wnt11 regulates cardiac chamber development and disease during
perinatal maturation
JCI insight,
2017; 2(17):
517-532.
Nicolas Gaël, Sanchez-Contreras Monica, Ramos Eliana Marisa, Lemos Roberta R, Ferreira Joana, Moura Denis, Sobrido Maria J, Richard Anne-Claire, Lopez Alma Rosa, Legati Andrea, Deleuze Jean-François, Boland Anne, Quenez Olivier, Krystkowiak Pierre, Favrole Pascal, Geschwind Daniel H, Aran Adi, Segel Reeval, Levy-Lahad Ephrat, Dickson Dennis W, Coppola Giovanni, Rademakers Rosa, de Oliveira João R M
Brain calcifications and PCDH12 variants
Neurology. Genetics,
2017; 3(4):
e166.
Lisi Véronique, Singh Bhagat, Giroux Michel, Guzman Elmer, Painter Michio W, Cheng Yung-Chih, Huebner Eric, Coppola Giovanni, Costigan Michael, Woolf Clifford J, Kosik Kenneth S
Enhanced Neuronal Regeneration in the CAST/Ei Mouse Strain Is Linked
to Expression of Differentiation Markers after Injury
Cell reports,
2017; 20(5):
1136-1147.
Chai Hua, Diaz-Castro Blanca, Shigetomi Eiji, Monte Emma, Octeau J Christopher, Yu Xinzhu, Cohn Whitaker, Rajendran Pradeep S, Vondriska Thomas M, Whitelegge Julian P, Coppola Giovanni, Khakh Baljit S
Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic,
Morphological, and Functional Evidence
Neuron,
2017; 95(3):
531-549.e9.
Huang Alden Y, Yu Dongmei, Davis Lea K, Sul Jae Hoon, Tsetsos Fotis, Ramensky Vasily, Zelaya Ivette, Ramos Eliana Marisa, Osiecki Lisa, Chen Jason A, McGrath Lauren M, Illmann Cornelia, Sandor Paul, Barr Cathy L, Grados Marco, Singer Harvey S, Nöthen Markus M, Hebebrand Johannes, King Robert A, Dion Yves, Rouleau Guy, Budman Cathy L, Depienne Christel, Worbe Yulia, Hartmann Andreas, Müller-Vahl Kirsten R, Stuhrmann Manfred, Aschauer Harald, Stamenkovic Mara, Schloegelhofer Monika, Konstantinidis Anastasios, Lyon Gholson J, McMahon William M, Barta Csaba, Tarnok Zsanett, Nagy Peter, Batterson James R, Rizzo Renata, Cath Danielle C, Wolanczyk Tomasz, Berlin Cheston, Malaty Irene A, Okun Michael S, Woods Douglas W, Rees Elliott, Pato Carlos N, Pato Michele T, Knowles James A, Posthuma Danielle, Pauls David L, Cox Nancy J, Neale Benjamin M, Freimer Nelson B, Paschou Peristera, Mathews Carol A, Scharf Jeremiah M, Coppola Giovanni, Coppola Giovanni, Coppola Giovanni
Rare Copy Number Variants in NRXN1 and CNTN6 Increase Risk for
Tourette Syndrome
Neuron,
2017; 94(6):
1101-1111.e7.
Norsworthy Michael W, Bei Fengfeng, Kawaguchi Riki, Wang Qing, Tran Nicholas M, Li Yi, Brommer Benedikt, Zhang Yiming, Wang Chen, Sanes Joshua R, Coppola Giovanni, He Zhigang
Sox11 Expression Promotes Regeneration of Some Retinal Ganglion Cell
Types but Kills Others
Neuron,
2017; 94(6):
1112-1120.e4.
Willsey A Jeremy, Fernandez Thomas V, Yu Dongmei, King Robert A, Dietrich Andrea, Xing Jinchuan, Sanders Stephan J, Mandell Jeffrey D, Huang Alden Y, Richer Petra, Smith Louw, Dong Shan, Samocha Kaitlin E, Samocha Kaitlin E, Samocha Kaitlin E, Neale Benjamin M, Coppola Giovanni, Mathews Carol A, Tischfield Jay A, Scharf Jeremiah M, State Matthew W, Heiman Gary A
De Novo Coding Variants Are Strongly Associated with Tourette
Disorder
Neuron,
2017; 94(3):
486-499.e9.
Fernández-Fournier Mireya, Perry David C, Tartaglia Maria Carmela, de May Mary, Boxer Adam, Coppola Giovanni, Christine Chadwick W, Huang Eric J, Seeley William W, Miller Bruce L, DeArmond Steven J, Grinberg Lea T, Geschwind Michael D
Precipitous Deterioration of Motor Function, Cognition, and Behavior
JAMA neurology,
2017; 74(5):
591-596.
Lopez Ana, Lee Suzee E, Wojta Kevin, Ramos Eliana Marisa, Klein Eric, Chen Jason, Boxer Adam L, Gorno-Tempini Maria Luisa, Geschwind Daniel H, Schlotawa Lars, Ogryzko Nikolay V, Bigio Eileen H, Rogalski Emily, Weintraub Sandra, Mesulam Marsel M, Mesulam Marsel M, Fleming Angeleen, Coppola Giovanni, Miller Bruce L, Rubinsztein David C
A152T tau allele causes neurodegeneration that can be ameliorated in a
zebrafish model by autophagy induction
Brain : a journal of neurology,
2017; 140(4):
1128-1146.
Yokoyama Jennifer S, Marx Gabe, Brown Jesse A, Bonham Luke W, Wang Dan, Coppola Giovanni, Seeley William W, Rosen Howard J, Miller Bruce L, Kramer Joel H, Dubal Dena B
Systemic klotho is associated with KLOTHO variation and predicts
intrinsic cortical connectivity in healthy human aging
Brain imaging and behavior,
2017; 11(2):
391-400.
Steele Natasha Z R, Carr Jessie S, Bonham Luke W, Geier Ethan G, Damotte Vincent, Miller Zachary A, Desikan Rahul S, Boehme Kevin L, Mukherjee Shubhabrata, Crane Paul K, Kauwe John S K, Kramer Joel H, Miller Bruce L, Coppola Giovanni, Hollenbach Jill A, Huang Yadong, Yokoyama Jennifer S
Fine-mapping of the human leukocyte antigen locus as a risk factor for
Alzheimer disease: A case-control study
PLoS medicine,
2017; 14(3):
e1002272.
Fong Jamie C, Rojas Julio C, Bang Jee, Legati Andrea, Rankin Katherine P, Forner Sven, Miller Zachary A, Karydas Anna M, Coppola Giovanni, Grouse Carrie K, Ralph Jeffrey, Miller Bruce L, Geschwind Michael D
Genetic Prion Disease Caused by PRNP Q160X Mutation Presenting with an
Orbitofrontal Syndrome, Cyclic Diarrhea, and Peripheral Neuropathy
Journal of Alzheimer's disease : JAD,
2017; 55(1):
249-258.
Chen Jason, Yu Jin-Tai, Wojta Kevin, Wang Hui-Fu, Zetterberg Henrik, Blennow Kaj, Yokoyama Jennifer S, Weiner Michael W, Kramer Joel H, Rosen Howard, Miller Bruce L, Coppola Giovanni, Boxer Adam L, Boxer Adam L
Genome-wide association study identifies MAPT locus influencing human
plasma tau levels
Neurology,
2017; 88(7):
669-676.
Bonham Luke W, Sirkis Daniel W, Fan Jia, Aparicio Renan E, Tse Marian, Ramos Eliana Marisa, Wang Qing, Coppola Giovanni, Rosen Howard J, Miller Bruce L, Yokoyama Jennifer S
Identification of a rare coding variant in TREM2 in a Chinese
individual with Alzheimer's disease
Neurocase,
2017; 23(1):
65-69.
Liu Collin Y, Ohki Yu, Tomita Taisuke, Osawa Satoko, Reed Bruce R, Jagust William, Van Berlo Victoria, Jin Lee-Way, Chui Helena C, Coppola Giovanni, Ringman John M
Two Novel Mutations in the First Transmembrane Domain of Presenilin1
Cause Young-Onset Alzheimer's Disease
Journal of Alzheimer's disease : JAD,
2017; 58(4):
1035-1041.
Wendelken Lauren A, Jahanshad Neda, Rosen Howard J, Busovaca Edgar, Allen Isabel, Coppola Giovanni, Adams Collin, Rankin Katherine P, Milanini Benedetta, Clifford Katherine, Wojta Kevin, Nir Talia M, Gutman Boris A, Thompson Paul M, Valcour Victor
ApoE ε4 Is Associated With Cognition, Brain Integrity, and Atrophy in
HIV Over Age 60
Journal of acquired immune deficiency syndromes (1999),
2016; 73(4):
426-432.
Wang Xin, Hao Limin, Saur Taixiang, Joyal Katelyn, Zhao Ying, Zhai Desheng, Li Jie, Pribadi Mochtar, Coppola Giovanni, Cohen Bruce M, Buttner Edgar A
Forward Genetic Screen in Caenorhabditis elegans Suggests F57A10.2 and
acp-4 As Suppressors of C9ORF72 Related Phenotypes
Frontiers in molecular neuroscience,
2016; 9(11):
113.
Vossel Keith A, Ranasinghe Kamalini G, Beagle Alexander J, Mizuiri Danielle, Honma Susanne M, Dowling Anne F, Darwish Sonja M, Van Berlo Victoria, Barnes Deborah E, Mantle Mary, Karydas Anna M, Coppola Giovanni, Roberson Erik D, Miller Bruce L, Garcia Paul A, Kirsch Heidi E, Mucke Lennart, Nagarajan Srikantan S
Incidence and impact of subclinical epileptiform activity in
Alzheimer's disease
Annals of neurology,
2016; 80(6):
858-870.
Miller Zachary A, Sturm Virginia E, Camsari Gamze Balci, Karydas Anna, Yokoyama Jennifer S, Grinberg Lea T, Boxer Adam L, Rosen Howard J, Rankin Katherine P, Gorno-Tempini Maria Luisa, Coppola Giovanni, Geschwind Daniel H, Rademakers Rosa, Seeley William W, Graff-Radford Neill R, Miller Bruce L
Increased prevalence of autoimmune disease within C9 and FTD/MND
cohorts: Completing the picture
Neurology(R) neuroimmunology & neuroinflammation,
2016; 3(6):
e301.
Vatsavayai Sarat C, Yoon Soo Jin, Gardner Raquel C, Gendron Tania F, Vargas Jose Norberto S, Trujillo Andrew, Pribadi Mochtar, Phillips Joanna J, Gaus Stephanie E, Hixson John D, Garcia Paul A, Rabinovici Gil D, Coppola Giovanni, Geschwind Daniel H, Petrucelli Leonard, Miller Bruce L, Seeley William W
Timing and significance of pathological features in C9orf72
expansion-associated frontotemporal dementia
Brain : a journal of neurology,
2016; 139(Pt 12):
3202-3216.
Soosman Steffan K, Joseph-Mathurin Nelly, Braskie Meredith N, Bordelon Yvette M, Wharton David, Casado Maria, Coppola Giovanni, McCallum Holly, Nuwer Marc, Coutin-Churchman Pedro, Apostolova Liana G, Benzinger Tammie, Ringman John M
Widespread white matter and conduction defects in PSEN1-related
spastic paraparesis
Neurobiology of aging,
2016; 47(11):
201-209.
Touma Marlin, Kang Xuedong, Zhao Yan, Cass Ashley A, Gao Fuying, Biniwale Reshma, Coppola Giovanni, Xiao Xinshu, Reemtsen Brian, Wang Yibin
Decoding the Long Noncoding RNA During Cardiac Maturation: A Roadmap
for Functional Discovery
Circulation. Cardiovascular genetics,
2016; 9(5):
395-407.
Laks Dan R, Crisman Thomas J, Shih Michelle Y S, Mottahedeh Jack, Gao Fuying, Sperry Jantzen, Garrett Matthew C, Yong William H, Cloughesy Timothy F, Liau Linda M, Lai Albert, Coppola Giovanni, Kornblum Harley I
Large-scale assessment of the gliomasphere model system
Neuro-oncology,
2016; 18(10):
1367-78.
Ranasinghe Kamalini G, Rankin Katherine P, Pressman Peter S, Perry David C, Lobach Iryna V, Seeley William W, Coppola Giovanni, Karydas Anna M, Grinberg Lea T, Shany-Ur Tal, Lee Suzee E, Rabinovici Gil D, Rosen Howard J, Gorno-Tempini Maria Luisa, Boxer Adam L, Miller Zachary A, Chiong Winston, DeMay Mary, Kramer Joel H, Possin Katherine L, Sturm Virginia E, Bettcher Brianne M, Neylan Michael, Zackey Diana D, Nguyen Lauren A, Ketelle Robin, Block Nikolas, Wu Teresa Q, Dallich Alison, Russek Natanya, Caplan Alyssa, Geschwind Daniel H, Vossel Keith A, Miller Bruce L
Distinct Subtypes of Behavioral Variant Frontotemporal Dementia Based
on Patterns of Network Degeneration
JAMA neurology,
2016; 73(9):
1078-88.
Silva M Catarina, Cheng Chialin, Mair Waltraud, Almeida Sandra, Fong Helen, Biswas M Helal U, Zhang Zhijun, Huang Yadong, Temple Sally, Coppola Giovanni, Geschwind Daniel H, Karydas Anna, Miller Bruce L, Kosik Kenneth S, Gao Fen-Biao, Steen Judith A, Haggarty Stephen J
Human iPSC-Derived Neuronal Model of Tau-A152T Frontotemporal Dementia
Reveals Tau-Mediated Mechanisms of Neuronal Vulnerability
Stem cell reports,
2016; 7(3):
325-340.
Sirkis Daniel W, Bonham Luke W, Aparicio Renan E, Geier Ethan G, Ramos Eliana Marisa, Wang Qing, Karydas Anna, Miller Zachary A, Miller Bruce L, Coppola Giovanni, Yokoyama Jennifer S
Rare TREM2 variants associated with Alzheimer's disease display
reduced cell surface expression
Acta neuropathologica communications,
2016; 4(1):
98.
Horvath Steve, Langfelder Peter, Kwak Seung, Aaronson Jeff, Rosinski Jim, Vogt Thomas F, Eszes Marika, Faull Richard L M, Curtis Maurice A, Waldvogel Henry J, Choi Oi-Wa, Tung Spencer, Vinters Harry V, Coppola Giovanni, Yang X William
Huntington's disease accelerates epigenetic aging of human brain and
disrupts DNA methylation levels
Aging,
2016; 8(7):
1485-512.
Peterson Christine B, Service Susan K, Jasinska Anna J, Gao Fuying, Zelaya Ivette, Teshiba Terri M, Bearden Carrie E, Cantor Rita M, Reus Victor I, Macaya Gabriel, López-Jaramillo Carlos, Bogomolov Marina, Benjamini Yoav, Eskin Eleazar, Coppola Giovanni, Freimer Nelson B, Sabatti Chiara
Characterization of Expression Quantitative Trait Loci in Pedigrees
from Colombia and Costa Rica Ascertained for Bipolar Disorder
PLoS genetics,
2016; 12(5):
e1006046.
Lui Hansen, Zhang Jiasheng, Makinson Stefanie R, Cahill Michelle K, Kelley Kevin W, Huang Hsin-Yi, Shang Yulei, Oldham Michael C, Martens Lauren Herl, Gao Fuying, Coppola Giovanni, Sloan Steven A, Hsieh Christine L, Kim Charles C, Bigio Eileen H, Weintraub Sandra, Mesulam Marek-Marsel, Rademakers Rosa, Mackenzie Ian R, Seeley William W, Karydas Anna, Miller Bruce L, Borroni Barbara, Ghidoni Roberta, Farese Robert V, Paz Jeanne T, Barres Ben A, Huang Eric J
Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by
Microglia via Complement Activation
Cell,
2016; 165(4):
921-35.
Omura Takao, Omura Kumiko, Tedeschi Andrea, Riva Priscilla, Painter Michio W, Rojas Leticia, Martin Joshua, Lisi Véronique, Huebner Eric A, Latremoliere Alban, Yin Yuqin, Barrett Lee B, Singh Bhagat, Lee Stella, Crisman Tom, Gao Fuying, Li Songlin, Kapur Kush, Geschwind Daniel H, Kosik Kenneth S, Coppola Giovanni, He Zhigang, Carmichael S Thomas, Benowitz Larry I, Costigan Michael, Woolf Clifford J
Robust Axonal Regeneration Occurs in the Injured CAST/Ei Mouse CNS
Neuron,
2016; 90(3):
662.
Anderson Mark A, Burda Joshua E, Ren Yilong, Ao Yan, O'Shea Timothy M, Kawaguchi Riki, Coppola Giovanni, Khakh Baljit S, Deming Timothy J, Sofroniew Michael V
Astrocyte scar formation aids central nervous system axon
regeneration
Nature,
2016; 532(7598):
195-200.
Langfelder Peter, Cantle Jeffrey P, Chatzopoulou Doxa, Wang Nan, Gao Fuying, Al-Ramahi Ismael, Lu Xiao-Hong, Ramos Eliana Marisa, El-Zein Karla, Zhao Yining, Deverasetty Sandeep, Tebbe Andreas, Schaab Christoph, Lavery Daniel J, Howland David, Kwak Seung, Botas Juan, Aaronson Jeffrey S, Rosinski Jim, Coppola Giovanni, Horvath Steve, Yang X William
Integrated genomics and proteomics define huntingtin CAG
length-dependent networks in mice
Nature neuroscience,
2016; 19(4):
623-33.
Chandran Vijayendran, Coppola Giovanni, Nawabi Homaira, Omura Takao, Versano Revital, Huebner Eric A, Zhang Alice, Costigan Michael, Yekkirala Ajay, Barrett Lee, Blesch Armin, Michaelevski Izhak, Davis-Turak Jeremy, Gao Fuying, Langfelder Peter, Horvath Steve, He Zhigang, Benowitz Larry, Fainzilber Mike, Tuszynski Mark, Woolf Clifford J, Geschwind Daniel H
A Systems-Level Analysis of the Peripheral Nerve Intrinsic Axonal
Growth Program
Neuron,
2016; 89(5):
956-70.
Ramirez Leslie M, Goukasian Naira, Porat Shai, Hwang Kristy S, Eastman Jennifer A, Hurtz Sona, Wang Benjamin, Vang Nouchee, Sears Renee, Klein Eric, Coppola Giovanni, Apostolova Liana G
Common variants in ABCA7 and MS4A6A are associated with cortical and
hippocampal atrophy
Neurobiology of aging,
2016; 39(3):
82-9.
Ringman John M, Monsell Sarah, Ng Denise W, Zhou Yan, Nguyen Andy, Coppola Giovanni, Van Berlo Victoria, Mendez Mario F, Tung Spencer, Weintraub Sandra, Mesulam Marek-Marsel, Bigio Eileen H, Gitelman Darren R, Fisher-Hubbard Amanda O, Albin Roger L, Vinters Harry V
Neuropathology of Autosomal Dominant Alzheimer Disease in the National
Alzheimer Coordinating Center Database
Journal of neuropathology and experimental neurology,
2016; 75(3):
284-90.
Karuppagounder Saravanan S, Alim Ishraq, Khim Soah J, Bourassa Megan W, Sleiman Sama F, John Roseleen, Thinnes Cyrille C, Yeh Tzu-Lan, Demetriades Marina, Neitemeier Sandra, Cruz Dana, Gazaryan Irina, Killilea David W, Morgenstern Lewis, Xi Guohua, Keep Richard F, Schallert Timothy, Tappero Ryan V, Zhong Jian, Cho Sunghee, Maxfield Frederick R, Holman Theodore R, Culmsee Carsten, Fong Guo-Hua, Su Yijing, Ming Guo-li, Song Hongjun, Cave John W, Schofield Christopher J, Colbourne Frederick, Coppola Giovanni, Ratan Rajiv R
Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates
ATF4-dependent neuronal death and improves outcomes after brain
hemorrhage in several rodent models
Science translational medicine,
2016; 8(328):
328ra29.
Naasan Georges, Rabinovici Gil D, Ghosh Pia, Elofson Jonathan D, Miller Bruce L, Coppola Giovanni, Karydas Anna, Fong Jamie, Perry David, Lee Suzee E, Yokoyama Jennifer S, Seeley William W, Kramer Joel H, Weiner Michael W, Schuff Norbert, Jagust William J, Grinberg Lea T, Pribadi Mochtar, Yang Zhongan, Sears Renee, Klein Eric, Wojta Kevin, Rosen Howard J
Amyloid in dementia associated with familial FTLD: not an innocent
bystander
Neurocase,
2016; 22(1):
76-83.
Schroeder Analyne M, Wang Huei Bin, Park Saemi, Jordan Maria C, Gao Fuying, Coppola Giovanni, Fishbein Michael C, Roos Kenneth P, Ghiani Cristina A, Colwell Christopher S
Cardiac Dysfunction in the BACHD Mouse Model of Huntington's Disease
PloS one,
2016; 11(1):
e0147269.
Sha Sharon J, Khazenzon Anna M, Ghosh Pia M, Rankin Katherine P, Pribadi Mochtar, Coppola Giovanni, Geschwind Daniel H, Rabinovici Gil D, Miller Bruce L, Lee Suzee E
Early-onset Alzheimer's disease versus frontotemporal dementia:
resolution with genetic diagnoses?
Neurocase,
2016; 22(2):
161-7.
Hodgson Karen, Tansey Katherine E, Powell Timothy R, Coppola Giovanni, Uher Rudolf, Zvezdana Dernovšek Mojca, Mors Ole, Hauser Joanna, Souery Daniel, Maier Wolfgang, Henigsberg Neven, Rietschel Marcella, Placentino Anna, Aitchison Katherine J, Craig Ian W, Farmer Anne E, Breen Gerome, McGuffin Peter, Dobson Richard
Transcriptomics and the mechanisms of antidepressant efficacy
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology,
2016; 26(1):
105-12.
Li Songlin, Nie Esther H, Yin Yuqin, Benowitz Larry I, Tung Spencer, Vinters Harry V, Bahjat F Rena, Stenzel-Poore Mary P, Kawaguchi Riki, Coppola Giovanni, Carmichael S Thomas
GDF10 is a signal for axonal sprouting and functional recovery after
stroke
Nature neuroscience,
2015; 18(12):
1737-45.
Ring Karen L, An Mahru C, Zhang Ningzhe, O'Brien Robert N, Ramos Eliana Marisa, Gao Fuying, Atwood Robert, Bailus Barbara J, Melov Simon, Mooney Sean D, Coppola Giovanni, Ellerby Lisa M
Genomic Analysis Reveals Disruption of Striatal Neuronal Development
and Therapeutic Targets in Human Huntington's Disease Neural Stem
Cells
Stem cell reports,
2015; 5(6):
1023-1038.
Ng Adeline S L, Sias Ana C, Pressman Peter S, Fong Jamie C, Karydas Anna M, Zanto Theodore P, De May Mary, Coppola Giovanni, Geschwind Daniel H, Miller Bruce L, Lee Suzee E
Young-onset frontotemporal dementia in a homozygous tau R406W mutation
carrier
Annals of clinical and translational neurology,
2015; 2(12):
1124-8.
Becherel Olivier J, Sun Jane, Yeo Abrey J, Nayler Sam, Fogel Brent L, Gao Fuying, Coppola Giovanni, Criscuolo Chiara, De Michele Giuseppe, Wolvetang Ernst, Lavin Martin F
A new model to study neurodegeneration in ataxia oculomotor apraxia
type 2
Human molecular genetics,
2015; 24(20):
5759-74.
Nicolas Gaël, Charbonnier Camille, de Lemos Roberta Rodrigues, Richard Anne-Claire, Guillin Olivier, Wallon David, Legati Andrea, Geschwind Daniel, Coppola Giovanni, Frebourg Thierry, Campion Dominique, de Oliveira João Ricardo Mendes, Hannequin Didier, Hannequin Didier
Brain calcification process and phenotypes according to age and sex:
Lessons from SLC20A2, PDGFB, and PDGFRB mutation carriers
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics,
2015; 168(7):
586-94.
Lehmann Manja, Madison Cindee, Ghosh Pia M, Miller Zachary A, Greicius Michael D, Kramer Joel H, Coppola Giovanni, Miller Bruce L, Jagust William J, Gorno-Tempini Maria L, Seeley William W, Rabinovici Gil D
Loss of functional connectivity is greater outside the default mode
network in nonfamilial early-onset Alzheimer's disease variants
Neurobiology of aging,
2015; 36(10):
2678-86.
Mesquita Sandro Dá, Ferreira Ana C, Gao Fuying, Coppola Giovanni, Geschwind Daniel H, Sousa João C, Correia-Neves Margarida, Sousa Nuno, Palha Joana A, Marques Fernanda
The choroid plexus transcriptome reveals changes in type I and II
interferon responses in a mouse model of Alzheimer's disease
Brain, behavior, and immunity,
2015; 49(7):
280-92.
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Mutations in rare ataxia genes are uncommon causes of sporadic
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Lipocalin 2 is present in the EAE brain and is modulated by
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The BMP coreceptor RGMb promotes while the endogenous BMP antagonist
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A gene expression phenotype in lymphocytes from Friedreich ataxia
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Distinctive genetic and clinical features of CMT4J: a severe
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Mithramycin is a gene-selective Sp1 inhibitor that identifies a
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Suberoylanilide hydroxamic acid (vorinostat) up-regulates progranulin
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Signaling to transcription networks in the neuronal retrograde injury
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Human-specific transcriptional regulation of CNS development genes by
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Criscuolo Chiara, Filla Alessandro, Coppola Giovanni, Rinaldi Carlo, Carbone Rosa, Pinto Stefano, Wang Qing, de Leva Maria Fulvia, Salvatore Elena, Banfi Sandro, Brunetti Arturo, Quarantelli Mario, Geschwind Daniel H, Pappatà Sabina, De Michele Giuseppe
Two novel CYP7B1 mutations in Italian families with SPG5: a clinical
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2009; 256(8):
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Coppola Giovanni, Marmolino Daniele, Lu Daning, Wang Qing, Cnop Miriam, Rai Myriam, Acquaviva Fabio, Cocozza Sergio, Pandolfo Massimo, Geschwind Daniel H
Functional genomic analysis of frataxin deficiency reveals
tissue-specific alterations and identifies the PPARgamma pathway as a
therapeutic target in Friedreich's ataxia
Human molecular genetics,
2009; 18(13):
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Johnson Matthew B, Kawasawa Yuka Imamura, Mason Christopher E, Krsnik Zeljka, Coppola Giovanni, BogdanoviÄ Darko, Geschwind Daniel H, Mane Shrikant M, State Matthew W, Sestan Nenad
Functional and evolutionary insights into human brain development
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Nagahara Alan H, Merrill David A, Coppola Giovanni, Tsukada Shingo, Schroeder Brock E, Shaked Gideon M, Wang Ling, Blesch Armin, Kim Albert, Conner James M, Rockenstein Edward, Chao Moses V, Koo Edward H, Geschwind Daniel, Masliah Eliezer, Chiba Andrea A, Tuszynski Mark H
Neuroprotective effects of brain-derived neurotrophic factor in rodent
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Ratan Rajiv R, Siddiq Ambreena, Aminova Leila, Langley Brett, McConoughey Stephen, Karpisheva Ksenia, Lee Hsin-Hwa, Carmichael Thomas, Kornblum Harley, Coppola Giovanni, Geschwind Daniel H, Hoke Ahmet, Smirnova Natalya, Rink Cameron, Roy Sashwati, Sen Chandan, Beattie Michael S, Hart Ron P, Grumet Martin, Sun Dongming, Freeman Robert S, Semenza Gregg L, Gazaryan Irina
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Carmichael S Thomas, Vespa Paul M, Saver Jeffery L, Coppola Giovanni, Geschwind Daniel H, Starkman Sidney, Miller Chad M, Kidwell Chelsea S, Liebeskind David S, Martin Neil A
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Thomas Elizabeth A, Coppola Giovanni, Desplats Paula A, Tang Bin, Soragni Elisabetta, Burnett Ryan, Gao Fuying, Fitzgerald Kelsey M, Borok Jenna F, Herman David, Geschwind Daniel H, Gottesfeld Joel M
The HDAC inhibitor 4b ameliorates the disease phenotype and
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Rosen Rebecca F, Farberg Aaron S, Gearing Marla, Dooyema Jeromy, Long Patrick M, Anderson Daniel C, Davis-Turak Jeremy, Coppola Giovanni, Geschwind Daniel H, Paré Jean-Francois, Duong Timothy Q, Hopkins William D, Preuss Todd M, Walker Lary C
Tauopathy with paired helical filaments in an aged chimpanzee
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Marques Fernanda, Rodrigues Ana-João, Sousa João C, Coppola Giovanni, Geschwind Daniel H, Sousa Nuno, Correia-Neves Margarida, Palha Joana A
Lipocalin 2 is a choroid plexus acute-phase protein
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Identification of the transcriptional targets of FOXP2, a gene linked
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Phenotypic variability associated with progranulin haploinsufficiency
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Neuropsychological assessment, quantitative MRI and ApoE gene
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Coppola Giovanni, Criscuolo Chiara, De Michele Giuseppe, Striano Salvatore, Barbieri Fabrizio, Striano Pasquale, Perretti Anna, Santoro Lucio, Brescia Morra Vincenzo, Saccà Francesco, Scarano Valentina, D'Adamo Adamo P, Banfi Sandro, Gasparini Paolo, Santorelli Filippo M, Lehesjoki Anna E, Filla Alessandro
Autosomal recessive progressive myoclonus epilepsy with ataxia and
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Varrone Andrea, Salvatore Elena, De Michele Giuseppe, Barone Paolo, Sansone Valeria, Pellecchia Maria Teresa, Castaldo Imma, Coppola Giovanni, Brunetti Arturo, Salvatore Marco, Pappatà Sabina, Filla Alessandro
Reduced striatal [123 I]FP-CIT binding in SCA2 patients without
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Variable phenotype in a P102L Gerstmann-Sträussler-Scheinker Italian
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