Timothy Hales, Ph.D.
Work Phone Number:
George Washington University Medical Center
2300 Eyes St. NW
Washington, DC 20037
Visiting Associate Professor,
Hatos Center for Neuropharmacology
Dr. Tim Hales is a professor in the Department of Pharmacology and Physiology at the George Washington University. He earned his doctorate degree in pharmacology at the University of Dundee in Scotland, UK studying the mechanisms of the intravenous anesthetic agent propofol. During postdoctoral studies at UCLA Dr. Hales became interested in opioid receptor signaling. He became an Assistant Professor in Residence within the Department of Anesthesiology at UCLA in 1994. In 1997, Dr. Hales joined the faculty of the Department of Pharmacology at GWU and in 2006 became a Professor of Pharmacology and Physiology with a joint appointment in the Department of Anesthesiology and Critical Care Medicine. Dr. Hales' research is funded by grants from National Institute of General Medical Sciences, National Institute on Drug abuse, and the National Science Foundation.
Dr. Hales directs the Neuroscience Track of the Molecular Medicine PhD degree course within the Institute for Biomedical Sciences at GWU. He has mentored numerous anesthesiologists (residents and faculty), postdoctoral fellows, PhD students, and undergraduate students. His lab currently includes an Assistant Professor of Anesthesiology, two postdoctoral fellows, three graduate students and two undergraduate students.
Hales, T. G. Deeb, T. Z. Tang, H. Bollan, K. A. King, D. P. Johnson, S. J. Connolly, C. N.
An asymmetric contribution to gamma-aminobutyric type A receptor function of a conserved lysine within TM2-3 of alpha1, beta2, and gamma2 subunits
J Biol Chem,
Hales, T. G. Tang, H. Bollan, K. A. Johnson, S. J. King, D. P. McDonald, N. A. Cheng, A. Connolly, C. N.
The epilepsy mutation, gamma2(R43Q) disrupts a highly conserved inter-subunit contact site, perturbing the biogenesis of GABAA receptors
Mol Cell Neurosci,
Irnaten, M. Walwyn, W. M. Wang, J. Venkatesan, P. Evans, C. Chang, K. S. Andresen, M. C. Hales, T. G. Mendelowitz, D.
Pentobarbital enhances GABAergic neurotransmission to cardiac parasympathetic neurons, which is prevented by expression of GABA(A) epsilon subunit