Fawzia Bardag-Gorce, Ph.D.

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Work Titles
CTSI Member, CTSI
UCLA Assistant Researcher, Pathology and Laboratory Medicine
Education:
Degrees:
Ph.D.

Contact Information:

Work Email Address:

fgorce@lundquist.org


Work Phone Number:

310-222-2483

Mailing Address:

Main Office
1124 West Carson Street
Los Angeles, CA 90502


Publications:

A selected list of publications:

Zaouali Mohamed Amine, Bardag-Gorce Fawzia, Carbonell Teresa, Oliva Joan, Pantazi Eirini, Bejaoui Mohamed, Ben Abdennebi Hassen, Rimola Antoni, Roselló-Catafau Joan   Proteasome inhibitors protect the steatotic and non-steatotic liver graft against cold ischemia reperfusion injury Experimental and molecular pathology, 2013; 94(2): 352-9.
Osna Natalia A, Bardag-Gorce Fawzia, White Ronda L, Weinman Steven A, Donohue Terrence M, Kharbanda Kusum K   Ethanol and Hepatitis C Virus Suppress Peptide-MHC Class I Presentation in Hepatocytes by Altering Proteasome Function Alcoholism, clinical and experimental research, 2012; 93(1): .
Kharbanda Kusum K, Bardag-Gorce Fawzia, Barve Shirish, Molina Patricia E, Osna Natalia A   Impact of Altered Methylation in Cytokine Signaling and Proteasome Function in Alcohol and Viral-Mediated Diseases Alcoholism, clinical and experimental research, 2012; 93(1): .
Oliva Joan, French Samuel W, Li Jun, Bardag-Gorce Fawzia   Proteasome inhibitor treatment reduced fatty acid, triacylglycerol and cholesterol synthesis Experimental and molecular pathology, 2012; 93(1): 26-34.
Padrissa-Altés Susagna, Zaouali Mohamed Amine, Boncompagni Eleonora, Bonaccorsi-Riani Eliano, Carbonell Teresa, Bardag-Gorce Fawzia, Oliva Joan, French Samuel W, Bartrons Ramon, Roselló-Catafau Joan   The use of a reversible proteasome inhibitor in a model of Reduced-Size Orthotopic Liver transplantation in rats Experimental and molecular pathology, 2012; 93(1): 99-110.
Bardag-Gorce Fawzia, French Samuel W   Delta-aminolevulinic dehydratase is a proteasome interacting protein Experimental and molecular pathology, 2011; 91(2): 485-9.
Bardag-Gorce Fawzia   Proteasome inhibitor treatment in alcoholic liver disease World journal of gastroenterology : WJG, 2011; 17(20): 2558-62.
Bardag-Gorce Fawzia, Oliva Joan, Lin Andrew, Li Jun, French Barbara A, French Samuel W   Proteasome inhibitor up regulates liver antioxidative enzymes in rat model of alcoholic liver disease Experimental and molecular pathology, 2011; 90(1): 123-30.
Oliva Joan, Bardag-Gorce Fawzia, Tillman Brittany, French Samuel W   Protective effect of quercetin, EGCG, catechin and betaine against oxidative stress induced by ethanol in vitro Experimental and molecular pathology, 2011; 90(3): 295-9.
Kudo Lili C, Parfenova Liubov, Ren Guijie, Vi Nancy, Hui Maria, Ma Zhongcai, Lau Kimbley, Gray Michelle, Bardag-Gorce Fawzia, Wiedau-Pazos Martina, Hui Koon-Sea, Karsten Stanislav L   Puromycin-sensitive aminopeptidase (PSA/NPEPPS) impedes development of neuropathology in hPSA/TAU(P301L) double-transgenic mice Human molecular genetics, 2011; 20(9): 1820-33.
Oliva Joan, Bardag-Gorce Fawzia, Li Jun, French Barbara A, French Samuel W   S-adenosylmethionine prevents the up regulation of Toll-like receptor (TLR) signaling caused by chronic ethanol feeding in rats Experimental and molecular pathology, 2011; 90(3): 239-43.
French Samuel W, Oliva Joan, French Barbara A, Li Jun, Bardag-Gorce Fawzia   Alcohol, nutrition and liver cancer: role of Toll-like receptor signaling World journal of gastroenterology : WJG, 2010; 16(11): 1344-8.
Bardag-Gorce Fawzia   Effects of ethanol on the proteasome interacting proteins World journal of gastroenterology : WJG, 2010; 16(11): 1349-57.
Li Jun, Bardag-Gorce Fawzia, Oliva Joan, Dedes Jennifer, French Barbara A, French Samuel W   Gene expression modifications in the liver caused by binge drinking and S-adenosylmethionine feeding. The role of epigenetic changes Genes & nutrition, 2010; 5(2): 169-79.
Oliva Joan, Bardag-Gorce Fawzia, French Barbara A, Li Jun, French Samuel W   Independent phenotype of binuclear hepatocytes and cellular localization of UbD Experimental and molecular pathology, 2010; 89(2): 103-8.
French Samuel W, Bardag-Gorce Fawzia, Li Jun, French Barbara A, Oliva Joan   Mallory-Denk body pathogenesis revisited World journal of hepatology, 2010; 2(8): 295-301.
Bardag-Gorce Fawzia, Oliva Joan, Wong Wesley, Fong Stephanie, Li Jun, French Barbara A, French Samuel W   S-adenosylmethionine decreases the peak blood alcohol levels 3 h after an acute bolus of ethanol by inducing alcohol metabolizing enzymes in the liver Experimental and molecular pathology, 2010; 89(3): 217-21.
Tomasi Maria Lauda, Ramani Komal, Lopitz-Otsoa Fernando, Rodríguez Manuel S, Li Tony W H, Ko Kwangsuk, Yang Heping, Bardag-Gorce Fawzia, Iglesias-Ara Ainhoa, Feo Francesco, Pascale Maria Rosa, Mato José M, Lu Shelly C   S-adenosylmethionine regulates dual-specificity mitogen-activated protein kinase phosphatase expression in mouse and human hepatocytes Hepatology (Baltimore, Md.), 2010; 51(6): 2152-61.
Bardag-Gorce Fawzia, Oliva Joan, Li Jun, French Barbara A, French Samuel W   SAMe prevents the induction of the immunoproteasome and preserves the 26S proteasome in the DDC-induced MDB mouse model Experimental and molecular pathology, 2010; 88(3): 353-62.
Bardag-Gorce Fawzia, Oliva Joan, Lin Andrew, Li Jun, French Barbara A, French Samuel W   SAMe prevents the up regulation of toll-like receptor signaling in Mallory-Denk body forming hepatocytes Experimental and molecular pathology, 2010; 88(3): 376-9.
Oliva Joan, Bardag-Gorce Fawzia, Lin Andrew, French Barbara A, French Samuel W   The role of cytokines in UbD promoter regulation and Mallory-Denk body-like aggresomes Experimental and molecular pathology, 2010; 89(1): 1-8.
Oliva Joan, Bardag-Gorce Fawzia, Li Jun, French Barbara A, Nguyen Sheila K, Lu Shelly C, French Samuel W   Betaine prevents Mallory-Denk body formation in drug-primed mice by epigenetic mechanisms Experimental and molecular pathology, 2009; 86(2): 77-86.
Bousquet-Dubouch Marie-Pierre, Nguen Sheila, Bouyssié David, Burlet-Schiltz Odile, French Samuel W, Monsarrat Bernard, Bardag-Gorce Fawzia   Chronic ethanol feeding affects proteasome-interacting proteins Proteomics, 2009; 9(13): 3609-22.
Oliva Joan, Dedes Jennifer, Li Jun, French Samuel-W, Bardag-Gorce Fawzia   Epigenetics of proteasome inhibition in the liver of rats fed ethanol chronically World journal of gastroenterology : WJG, 2009; 15(6): 705-12.
Bardag-Gorce Fawzia   Nuclear effects of ethanol-induced proteasome inhibition in liver cells World journal of gastroenterology : WJG, 2009; 15(10): 1163-7.
Oliva Joan, Bardag-Gorce Fawzia, French Barbara A, Li Jun, French Samuel W   The regulation of non-coding RNA expression in the liver of mice fed DDC Experimental and molecular pathology, 2009; 87(1): 12-9.
Bardag-Gorce Fawzia, Oliva Joan, Villegas Jessica, Fraley Sara, Amidi Fataneh, Li Jun, Dedes Jennifer, French Barbara, French Samuel W   Epigenetic mechanisms regulate Mallory Denk body formation in the livers of drug-primed mice Experimental and molecular pathology, 2008; 84(2): 113-21.
Oliva Joan, Bardag-Gorce Fawzia, French Barbara A, Li Jun, McPhaul Laron, Amidi Fataneh, Dedes Jeniffer, Habibi Amir, Nguyen Sheila, French Samuel W   Fat10 is an epigenetic marker for liver preneoplasia in a drug-primed mouse model of tumorigenesis Experimental and molecular pathology, 2008; 84(2): 102-12.
Li Jun, Bardag-Gorce Fawzia, Dedes Jennifer, French Barbara Alan, Amidi Fataneh, Oliva Joan, French Samuel William   S-adenosylmethionine prevents Mallory Denk body formation in drug-primed mice by inhibiting the epigenetic memory Hepatology (Baltimore, Md.), 2008; 47(2): 613-24.
Oliva Joan, French Barbara A, Li Jun, Bardag-Gorce Fawzia, Fu Paul, French Samuel W   Sirt1 is involved in energy metabolism: the role of chronic ethanol feeding and resveratrol Experimental and molecular pathology, 2008; 85(3): 155-9.
Bardag-Gorce Fawzia, French Barbara A, Joyce Michael, Baires Mercedes, Montgomery Rosalyn O, Li Jun, French Samuel   Histone acetyltransferase p300 modulates gene expression in an epigenetic manner at high blood alcohol levels Experimental and molecular pathology, 2007; 82(2): 197-202.
Bardag-Gorce Fawzia, Dedes Jennifer, French Barbara A, Oliva Joan V, Li Jun, French Samuel W   Mallory body formation is associated with epigenetic phenotypic change in hepatocytes in vivo Experimental and molecular pathology, 2007; 83(2): 160-8.
Bardag-Gorce Fawzia, French Barbara A, Nan Li, Song Helen, Nguyen Sheila Khanh, Yong Holly, Dede Jennifer, French Samuel W   CYP2E1 induced by ethanol causes oxidative stress, proteasome inhibition and cytokeratin aggresome (Mallory body-like) formation Experimental and molecular pathology, 2006; 81(3): 191-201.
Bardag-Gorce Fawzia, French Barbara A, Dedes Jennifer, Li Jun, French Samuel W   Gene expression patterns of the liver in response to alcohol: in vivo and in vitro models compared Experimental and molecular pathology, 2006; 80(3): 241-51.
Nan Li, Dedes Jennifer, French Barbara A, Bardag-Gorce Fawzia, Li Jun, Wu Yong, French Samuel W   Mallory body (cytokeratin aggresomes) formation is prevented in vitro by p38 inhibitor Experimental and molecular pathology, 2006; 80(3): 228-40.
Nan Li, Bardag-Gorce Fawzia, Wu Yong, Li Jun, French Barbara A, French Samuel W   Mallory body forming cells express the preneoplastic hepatocyte phenotype Experimental and molecular pathology, 2006; 80(2): 109-18.
Gomes Aldrin V, Zong Chenggong, Edmondson Ricky D, Li Xiaohai, Stefani Enrico, Zhang Jun, Jones Richard C, Thyparambil Sheeno, Wang Guang-Wu, Qiao Xin, Bardag-Gorce Fawzia, Ping Peipei   Mapping the murine cardiac 26S proteasome complexes Circulation research, 2006; 99(4): 362-71.
Roomi M Waheed, Gaal Karl, Yuan Qi X, French Barbara A, Fu Paul, Bardag-Gorce Fawzia, French Samuel W   Preneoplastic liver cell foci expansion induced by thioacetamide toxicity in drug-primed mice Experimental and molecular pathology, 2006; 81(1): 8-14.
Zong Chenggong, Gomes Aldrin V, Drews Oliver, Li Xiaohai, Young Glen W, Berhane Beniam, Qiao Xin, French Samuel W, Bardag-Gorce Fawzia, Ping Peipei   Regulation of murine cardiac 20S proteasomes: role of associating partners Circulation research, 2006; 99(4): 372-80.
Bardag-Gorce Fawzia, Wilson L, Nan Li, Li Jun, French Barbara A, Morgan Timothy R, Morgan Kengathevy, French Samuel W   CYP2E1 inhibition enhances mallory body formation Experimental and molecular pathology, 2005; 78(3): 207-11.
French Barbara A, Dedes Jenniffer, Bardag-Gorce Fawzia, Li Jun, Wilson Latoyia, Fu Paul, Nan Li, French Samuel W   Microarray analysis of gene expression in the liver during the urinary ethanol cycle in rats fed ethanol intragastrically at a constant rate Experimental and molecular pathology, 2005; 79(2): 87-94.
Bardag-Gorce Fawzia, Francis Tricia, Nan Li, Li Jun, He Lue Yan, French Barbara A, French Samuel W   Modifications in P62 occur due to proteasome inhibition in alcoholic liver disease Life sciences, 2005; 77(20): 2594-602.
Nan Li, Wu Yong, Bardag-Gorce Fawzia, Li Jun, French Barbara A, Wilson La Toyia, Khanh Nguyen Sheila, French Samuel W   RNA interference of VCP/p97 increases Mallory body formation Experimental and molecular pathology, 2005; 78(1): 1-9.
Bardag-Gorce Fawzia, Li Jun, French Barbara A, French Samuel W   The effect of ethanol-induced CYP2E1 on proteasome activity: the role of 4-hydroxynonenal Experimental and molecular pathology, 2005; 78(2): 109-15.
Nan Li, Wu Yong, Bardag-Gorce Fawzia, Li Jun, French Barbaba A, Wilson La Toyia, French Samuel W   The p105/50 NF-kappaB pathway is essential for Mallory body formation Experimental and molecular pathology, 2005; 78(3): 198-206.
Wu Yong, Nan Li, Bardag-Gorce Fawzia, Li Jun, French Barbaba A, Wilson La Toyia, Dedes Jennifer, French Samuel W   The role of laminin-integrin signaling in triggering MB formation. An in vivo and in vitro study Experimental and molecular pathology, 2005; 79(1): 1-8.
Li Jun, French Barbara A, Fu Paul, Bardag-Gorce Fawzia, French Samuel W   Catecholamines are involved in the mechanism of the urinary alcohol level cycle in rats fed ethanol intragastrically at a constant rate Life sciences, 2004; 75(25): 3043-51.
Bardag-Gorce Fawzia, Venkatesh Ravi, Li Jun, French Barbara Alan, French Samuel William   Hyperphosphorylation of rat liver proteasome subunits: the effects of ethanol and okadaic acid are compared Life sciences, 2004; 75(5): 585-97.
Li Jun, French Barbara, Wu Yong, Vanketesh Ravi, Montgomery Rosalyn, Bardag-Gorce Fawzia, Kitto Jennifer, French Samuel W   Liver hypoxia and lack of recovery after reperfusion at high blood alcohol levels in the intragastric feeding model of alcohol liver disease Experimental and molecular pathology, 2004; 77(3): 184-92.
Bardag-Gorce Fawzia, Vu Jennifer, Nan Li, Riley Nora, Li Jun, French Samuel W   Proteasome inhibition induces cytokeratin accumulation in vivo Experimental and molecular pathology, 2004; 76(2): 83-9.
Wu Yong, Zhang Xiaoxue, Bardag-Gorce Fawzia, Robel Rose C V, Aguilo Jonathan, Chen Lixin, Zeng Ying, Hwang Kelly, French Samuel W, Lu Shelly C, Wan Yu-Jui Y   Retinoid X receptor alpha regulates glutathione homeostasis and xenobiotic detoxification processes in mouse liver Molecular pharmacology, 2004; 65(3): 550-7.
Bardag-Gorce Fawzia, Riley Nora E, Nan Li, Montgomery Rosalyn O, Li Jun, French Barbara A, Lue Yan H, French Samuel W   The proteasome inhibitor, PS-341, causes cytokeratin aggresome formation Experimental and molecular pathology, 2004; 76(1): 9-16.
Nan Li, Wu Yong, Bardag-Gorce Fawzia, Li Jun, French Barbara A, Fu Alan N, Francis Tricia, Vu Jennifer, French Samuel W   p62 is involved in the mechanism of Mallory body formation Experimental and molecular pathology, 2004; 77(3): 168-75.
Li Jun, French Barbara A, Fu Paul, Bardag-Gorce Fawzia, French Samuel W   Mechanism of the alcohol cyclic pattern: role of catecholamines American journal of physiology. Gastrointestinal and liver physiology, 2003; 285(2): G442-8.
Bardag-Gorce Fawzia, Li Jun, French Barbara Alan, French Samuel William   Ethanol withdrawal induced CYP2E1 degradation in vivo, blocked by proteasomal inhibitor PS-341 Free radical biology & medicine, 2002; 32(1): 17-21.
Bardag-Gorce Fawzia, French Barbara A, Li Jun, Riley Nora E, Yuan Qi X, Valinluck Vimonrat, Fu Paul, Ingelman-Sundberg Magnus, Yoon Seokjoo, French Samuel W   The importance of cycling of blood alcohol levels in the pathogenesis of experimental alcoholic liver disease in rats Gastroenterology, 2002; 123(1): 325-35.
Bardag-Gorce Fawzia, van Leeuwen Frederik Willen, Nguyen Victoria, French Barbara Alan, Li Jun, Riley Nora, McPhaul Laron Wilson, Lue Yan He, French Samuel William   The role of the ubiquitin-proteasome pathway in the formation of mallory bodies Experimental and molecular pathology, 2002; 73(2): 75-83.

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