Christopher Logg, Ph.D.


Work Titles
UCLA Associate Director, CURE Vector Core Facility Assistant Adjunct Professor, Medicine
Education:
Degrees:
Ph.D., University of Southern California
B.A., University of California, Berkeley

Contact Information:

Email Address:

logg@ucla.edu


Publications:

A selected list of publications:

Perez Omar D, Logg Christopher R, Hiraoka Kei, Diago Oscar, Burnett Ryan, Inagaki Akihito, Jolson Dawn, Amundson Karin, Buckley Taylor, Lohse Dan, Lin Amy, Burrascano Cindy, Ibanez Carlos, Kasahara Noriyuki, Gruber Harry E, Jolly Douglas J   Design and selection of Toca 511 for clinical use: modified retroviral replicating vector with improved stability and gene expression Molecular Therapy, 2012; 20(9): 1689-98.
Lemp Nathan A, Hiraoka Kei, Kasahara Noriyuki, Logg Christopher R   Cryptic transcripts from a ubiquitous plasmid origin of replication confound tests for cis-regulatory function Nucleic Acids Research, 2012; 40(15): 7280-90.
Logg Christopher R, Robbins Joan M, Jolly Douglas J, Gruber Harry E, Kasahara Noriyuki   Retroviral replicating vectors in cancer Methods in Enzymology, 2012; 507: 199-228.
Tai C-K, Wang W, Lai Y-H, Logg CR, Parker WB, Li Y-F, Hong JS, Sorscher EJ, Chen TC, Kasahara N   Enhanced efficiency of prodrug activation therapy by tumor-selective replicating retrovirus vectors armed with the Escherichia coli purine nucleoside phosphorylase gene Cancer Gene Therapy, 2010; 17(9): 614-23.
Kimura Takahiro, Hiraoka Kei, Kasahara Noriyuki, Logg Christopher R   Optimization of enzyme-substrate pairing for bioluminescence imaging of gene transfer using Renilla and Gaussia luciferases Journal of Gene Medicine, 2010; 12(6): 528-37.
Haga Kazunori, Tomioka Atsushi, Liao Chun-Peng, Kimura Takahiro, Matsumoto Hiroshi, Ohno Izumi, Hermann Kip, Logg Christopher R, Jiao Jing, Tanaka Motoyoshi, Hirao Yoshihiko, Wu Hong, Kruse Carol A, Roy-Burman Pradip, Kasahara Noriyuki   PTEN knockout prostate cancer as a model for experimental immunotherapy Journal of Urology, 2009; 181(1): 354-62.
Baranick Brian T, Lemp Nathan A, Nagashima Jill, Hiraoka Kei, Kasahara Noriyuki, Logg Christopher R   Splicing mediates the activity of four putative cellular internal ribosome entry sites Proceedings of the National Academy of Sciences of the United States of America, 2008; 105(12): 4733-8.
Kikuchi Eiji, Menendez Silvia, Ozu Choichiro, Ohori Makoto, Cordon-Cardo Carlos, Logg Christopher R, Kasahara Noriyuki, Bochner Bernard H   Highly efficient gene delivery for bladder cancers by intravesically administered replication-competent retroviral vectors Clinical Cancer Research, 2007; 13(15 Pt 1): 4511-8.
Logg Christopher R, Baranick Brian T, Lemp Nathan A, Kasahara Noriyuki   Adaptive evolution of a tagged chimeric gammaretrovirus: identification of novel cis-acting elements that modulate splicing Journal of Molecular Biology, 2007; 369(5): 1214-29.
Hiraoka Kei, Kimura Takahiro, Logg Christopher R, Tai Chien-Kuo, Haga Kazunori, Lawson Gregory W, Kasahara Noriyuki   Therapeutic efficacy of replication-competent retrovirus vector-mediated suicide gene therapy in a multifocal colorectal cancer metastasis model Cancer Research, 2007; 67(11): 5345-53.
Kikuchi E, Menendez S, Ozu C, Ohori M, Cordon-Cardo C, Logg CR, Kasahara N, Bochner BH   Delivery of replication-competent retrovirus expressing Escherichia coli purine nucleoside phosphorylase increases the metabolism of the prodrug, fludarabine phosphate and suppresses the growth of bladder tumor xenografts Cancer Gene Therapy, 2007; 14(3): 279-86.
Haga K, Lemp NA, Logg CR, Nagashima J, Faure-Kumar E, Gomez GG, Kruse CA, Mendez R, Stripecke R, Kasahara N, Kasahara N, Cicciarelli JC   Permanent, lowered HLA class I expression using lentivirus vectors with shRNA constructs: Averting cytotoxicity by alloreactive T lymphocytes Transplantation Proceedings, 2006; 38(10): 3184-8.
Hiraoka Kei, Kimura Takahiro, Logg Christopher R, Kasahara Noriyuki   Tumor-selective gene expression in a hepatic metastasis model after locoregional delivery of a replication-competent retrovirus vector Clinical Cancer Research, 2006; 12(23): 7108-16.
Dalba Charlotte, Klatzmann David, Logg Christopher R, Kasahara Noriyuki   Beyond oncolytic virotherapy: replication-competent retrovirus vectors for selective and stable transduction of tumors Current Gene Therapy, 2005; 5(6): 655-67.
Logg Christopher R, Kasahara Noriyuki   Retrovirus-mediated gene transfer to tumors: utilizing the replicative power of viruses to achieve highly efficient tumor transduction in vivo Methods in Molecular Biology, 2004; 246(3): 499-525.
Tai Chien-Kuo, Logg Christopher R, Park Jinha M, Anderson W French, Press Michael F, Kasahara Noriyuki   Antibody-mediated targeting of replication-competent retroviral vectors Human Gene Therapy, 2003; 14(8): 789-802.
Logg CR, Logg A, Matusik RJ, Bochner BH, Kasahara N   Tissue-specific transcriptional targeting of a replication-competent retroviral vector Journal of Virology, 2002; 76(24): 12783-91.
Soifer Harris, Higo Collin, Logg Christopher R, Jih Lily Ja-Lu, Shichinohe Toshiaki, Harboe-Schmidt Erik, Mitani Kohnosuke, Kasahara Noriyuki   A novel, helper-dependent, adenovirus-retrovirus hybrid vector: stable transduction by a two-stage mechanism Molecular Therapy, 2002; 5(5 Pt 1): 599-608.
Chang Z, Pan J, Logg C, Kasahara N, Roy-Burman P   A replication-competent feline leukemia virus, subgroup A (FeLV-A), tagged with green fluorescent protein reporter exhibits in vitro biological properties similar to those of the parental FeLV-A Journal of Virology, 2001; 75(18): 8837-41.
Logg CR, Logg A, Tai CK, Cannon PM, Kasahara N   Genomic stability of murine leukemia viruses containing insertions at the Env-3' untranslated region boundary Journal of Virology, 2001; 75(15): 6989-98.
Logg CR, Tai C K, Logg A, Anderson WF, Kasahara N   A uniquely stable replication-competent retrovirus vector achieves efficient gene delivery in vitro and in solid tumors Human Gene Therapy, 2001; 12(8): 921-32.
Smith E, Redman RA, Logg CR, Coetzee GA, Kasahara N, Frenkel B   Glucocorticoids inhibit developmental stage-specific osteoblast cell cycle. Dissociation of cyclin A-cyclin-dependent kinase 2 from E2F4-p130 complexes The Journal of Biological Chemistry, 2000; 275(26): 19992-20001.

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