Elliot Landaw, M.D., Ph.D.

A Short Biography:

Dr. Elliot Landaw's research interests center on kinetic analysis, compartmental modeling, nonlinear estimation and optimization problems in pharmacokinetics, physiology and molecular biology. His methodological interests in parameter estimation, optimal/robust sampling designs and adaptive control for computational models address problems arising from a variety of collaborations with experimental and clinical groups.


Work Titles
CTSI Member, CTSI Investigator, Workforce Development
UCLA Member, JCCC Patients and Survivors Program Area Professor Emeritus, Biomathematics
Education:
Degrees:
M.D., University of Chicago, Chicago, Illinois, 1968 - 1972
Ph.D., University of California, Los Angeles, 1976 - 1980
B.A., Rutgers University, 1964 - 1968
Certifications:
Certifications:
1977 American Board of Pediatrics, General Pediatrics

Contact Information:

Work Email Address:

elandaw@biomath.ucla.edu


Website:

Web-Profile

Work Phone Number:

(310) 825-6743

Office Address:

UCLA Dept. Computational Medicine (home of graduate Biomathematics program)
David Geffen School of Medicine
621 Charles E. Young Drive South
Box 951766, Room 5303 Life Sciences
Los Angeles, CA 90095


Publications:

A selected list of publications:

Wen Andy Y, Landaw Elliot M, Ochoa Rachel, Cho Michelle, Chao Alex, Lawson Gregory, Sakamoto Kathleen M   Increased abscess formation and defective chemokine regulation in CREB transgenic mice PloS one, 2013; 8(2): e55866.
Federman Noah, Chan Jason, Nagy Jon O, Landaw Elliot M, McCabe Katelyn, Wu Anna M, Triche Timothy, Kang Hyunggyoo, Liu Bin, Marks James D, Denny Christopher T   Enhanced growth inhibition of osteosarcoma by cytotoxic polymerized liposomal nanoparticles targeting the alcam cell surface receptor Sarcoma, 2012; 2012(1): 126906.
Sandoval Salemiz, Kraus Christina, Cho Er-Chieh, Cho Michelle, Bies Juraj, Manara Elena, Accordi Benedetta, Landaw Elliot M, Wolff Linda, Pigazzi Martina, Sakamoto Kathleen M   Sox4 cooperates with CREB in myeloid transformation Blood, 2012; 120(1): 155-65.
Patel Mayank, Gonzalez Rodrigo, Halford Colin, Lewinski Michael A, Landaw Elliot M, Churchill Bernard M, Haake David A   Target-specific capture enhances sensitivity of electrochemical detection of bacterial pathogens Journal of clinical microbiology, 2011; 49(12): 4293-6.
Hernandez-Davies Jenny E, Zape Joan P, Landaw Elliot M, Tan Xiaolin, Presnell Ajia, Griffith Diana, Heinrich Michael C, Glaser Keith B, Sakamoto Kathleen M   The multitargeted receptor tyrosine kinase inhibitor linifanib (ABT-869) induces apoptosis through an Akt and glycogen synthase kinase 3β-dependent pathway Molecular cancer therapeutics, 2011; 10(6): 949-59.
Aldana-Masangkay Grace I, Rodriguez-Gonzalez Agustin, Lin Tara, Ikeda Alan K, Hsieh Yao-Te, Kim Yong-Mi, Lomenick Brett, Okemoto Kazuo, Landaw Elliot M, Wang Dongpeng, Mazitschek Ralph, Bradner James E, Sakamoto Kathleen M   Tubacin suppresses proliferation and induces apoptosis of acute lymphoblastic leukemia cells Leukemia & lymphoma, 2011; 52(8): 1544-55.
Ikeda Alan K, Judelson Dejah R, Federman Noah, Glaser Keith B, Landaw Elliot M, Denny Christopher T, Sakamoto Kathleen M   ABT-869 inhibits the proliferation of Ewing Sarcoma cells and suppresses platelet-derived growth factor receptor beta and c-KIT signaling pathways Molecular cancer therapeutics, 2010; 9(3): 653-60.
Cheng Jerry C, Kinjo Kentaro, Judelson Dejah R, Chang Jenny, Wu Winston S, Schmid Ingrid, Shankar Deepa B, Kasahara Noriyuki, Stripecke Renata, Bhatia Ravi, Landaw Elliot M, Sakamoto Kathleen M   CREB is a critical regulator of normal hematopoiesis and leukemogenesis Blood, 2008; 111(3): 1182-92.
Mastali Mitra, Babbitt Jane T, Li Yang, Landaw Elliot M, Gau Vincent, Churchill Bernard M, Haake David A   Optimal probe length and target location for electrochemical detection of selected uropathogens at ambient temperature Journal of clinical microbiology, 2008; 46(8): 2707-16.
Ivancic Vesna, Mastali Mitra, Percy Neil, Gornbein Jeffrey, Babbitt Jane T, Li Yang, Landaw Elliot M, Bruckner David A, Churchill Bernard M, Haake David A   Rapid antimicrobial susceptibility determination of uropathogens in clinical urine specimens by use of ATP bioluminescence Journal of clinical microbiology, 2008; 46(4): 1213-9.
Liao Joseph C, Mastali Mitra, Li Yang, Gau Vincent, Suchard Marc A, Babbitt Jane, Gornbein Jeffrey, Landaw Elliot M, McCabe Edward R B, Churchill Bernard M, Haake David A   Development of an advanced electrochemical DNA biosensor for bacterial pathogen detection The Journal of molecular diagnostics : JMD, 2007; 9(2): 158-68.
Skaggs Brian J, Gorre Mercedes E, Ryvkin Ann, Burgess Michael R, Xie Yongming, Han Yun, Komisopoulou Evangelia, Brown Lauren M, Loo Joseph A, Landaw Elliot M, Sawyers Charles L, Graeber Thomas G   Phosphorylation of the ATP-binding loop directs oncogenicity of drug-resistant BCR-ABL mutants Proceedings of the National Academy of Sciences of the United States of America, 2006; 103(51): 19466-71.
Liao Joseph C, Mastali Mitra, Gau Vincent, Suchard Marc A, Møller Annette K, Bruckner David A, Babbitt Jane T, Li Yang, Gornbein Jeffrey, Landaw Elliot M, McCabe Edward R B, Churchill Bernard M, Haake David A   Use of electrochemical DNA biosensors for rapid molecular identification of uropathogens in clinical urine specimens Journal of clinical microbiology, 2006; 44(2): 561-70.
Riedl Marc A, Landaw Elliot M, Saxon Andrew, Diaz-Sanchez David   Initial high-dose nasal allergen exposure prevents allergic sensitization to a neoantigen Journal of immunology (Baltimore, Md. : 1950), 2005; 174(11): 7440-5.
Kim G, Rajasekaran SA, Thomas G, Rosen EA, Landaw EM, Shintaku P, Lassman C, Said J, Rajasekaran AK   Renal clear-cell carcinoma: an ultrastructural study on the junctional complexes Histology and histopathology. , 2005; 20(1): 35-44.
Shankar Deepa B, Cheng Jerry C, Kinjo Kentaro, Federman Noah, Moore Theodore B, Gill Amandip, Rao Nagesh P, Landaw Elliot M, Sakamoto Kathleen M   The role of CREB as a proto-oncogene in hematopoiesis and in acute myeloid leukemia Cancer cell, 2005; 7(4): 351-62.
Countouriotis Athena, Landaw Elliot M, Naeim Faramarz, Moore Theodore B, Sakamoto Kathleen M   Comparison of bone marrow aspirates and biopsies in pediatric patients with ALL at days 7 and 14 of induction therapy Leukemia & lymphoma, 2004; 45(4): 745-7.
Crans-Vargas Heather N, Landaw Elliot M, Bhatia Smita, Sandusky George, Moore Theodore B, Sakamoto Kathleen M   Expression of cyclic adenosine monophosphate response-element binding protein in acute leukemia Blood, 2002; 99(7): 2617-9.
Yu Rong Chun, Hattis Dale, Landaw Elliot M, Froines John R   Toxicokinetic interaction of 2,5-hexanedione and methyl ethyl ketone Archives of toxicology, 2002; 75(11-12): 643-52.

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