Publications:
A selected list of publications:
Gharavi, N. M. Alva, J. A. Mouillesseaux, K. P. Lai, C. Yeh, M. Yeung, W. Johnson, J. Szeto, W. L. Hong, L. Fishbein, M. Wei, L. Pfeffer, L. M. Berliner, J. A.
Role of the Jak/STAT pathway in the regulation of interleukin-8 transcription by oxidized phospholipids in vitro and in atherosclerosis in vivo
J Biol Chem,
2007; 282(43):
31460-8.
Gharavi, N. M. Gargalovic, P. S. Chang, I. Araujo, J. A. Clark, M. J. Szeto, W. L. Watson, A. D. Lusis, A. J. Berliner, J. A.
High-density lipoprotein modulates oxidized phospholipid signaling in human endothelial cells from proinflammatory to anti-inflammatory
Arterioscler Thromb Vasc Biol,
2007; 27(6):
1346-53.
Zimman, A. Mouillesseaux, K. P. Le, T. Gharavi, N. M. Ryvkin, A. Graeber, T. G. Chen, T. T. Watson, A. D. Berliner, J. A.
Vascular endothelial growth factor receptor 2 plays a role in the activation of aortic endothelial cells by oxidized phospholipids
Arterioscler Thromb Vasc Biol,
2007; 27(2):
332-8.
Gargalovic, P. S. Imura, M. Zhang, B. Gharavi, N. M. Clark, M. J. Pagnon, J. Yang, W. P. He, A. Truong, A. Patel, S. Nelson, S. F. Horvath, S. Berliner, J. A. Kirchgessner, T. G. Lusis, A. J.
Identification of inflammatory gene modules based on variations of human endothelial cell responses to oxidized lipids
Proc Natl Acad Sci U S A,
2006; 103(34):
12741-6.
Gargalovic, P. S. Gharavi, N. M. Clark, M. J. Pagnon, J. Yang, W. P. He, A. Truong, A. Baruch-Oren, T. Berliner, J. A. Kirchgessner, T. G. Lusis, A. J.
The unfolded protein response is an important regulator of inflammatory genes in endothelial cells
Arterioscler Thromb Vasc Biol,
2006; 26(11):
2490-6.
Gharavi, N. M. Baker, N. A. Mouillesseaux, K. P. Yeung, W. Honda, H. M. Hsieh, X. Yeh, M. Smart, E. J. Berliner, J. A.
Role of endothelial nitric oxide synthase in the regulation of SREBP activation by oxidized phospholipids
Circ Res,
2006; 98(6):
768-76.
Yeh, M. Cole, A. L. Choi, J. Liu, Y. Tulchinsky, D. Qiao, J. H. Fishbein, M. C. Dooley, A. N. Hovnanian, T. Mouilleseaux, K. Vora, D. K. Yang, W. P. Gargalovic, P. Kirchgessner, T. Shyy, J. Y. Berliner, J. A.
Role for sterol regulatory element-binding protein in activation of endothelial cells by phospholipid oxidation products
Circ Res,
2004; 95(8):
780-8.
Yeh, M Cole, AL Choi, J Liu, Y Tulchinsky, D Qiao, JH Fishbein, MC Dooley, AN Hovnanian, T Mouilleseaux, K Vora, DK Yang, WP Gargalovic, P Kirchgessner, T Shyy, JY Berliner, JA
Role for sterol regulatory element-binding protein in activation of endothelial cells by phospholipid oxidation products
Circulation research. ,
2004; 95(8):
780-8.
Yeh, M. Gharavi, N. M. Choi, J. Hsieh, X. Reed, E. Mouillesseaux, K. P. Cole, A. L. Reddy, S. T. Berliner, J. A.
Oxidized phospholipids increase interleukin 8 (IL-8) synthesis by activation of the c-src/signal transducers and activators of transcription (STAT)3 pathway
J Biol Chem,
2004; 279(29):
30175-81.
Walton, K. A. Cole, A. L. Yeh, M. Subbanagounder, G. Krutzik, S. R. Modlin, R. L. Lucas, R. M. Nakai, J. Smart, E. J. Vora, D. K. Berliner, J. A.
Specific phospholipid oxidation products inhibit ligand activation of toll-like receptors 4 and 2
Arterioscler Thromb Vasc Biol,
2003; 23(7):
1197-203.
Yeh, M Leitinger, N de Martin, R Onai, N Matsushima, K Vora, DK Berliner, JA Reddy, ST
Increased transcription of IL-8 in endothelial cells is differentially regulated by TNF-alpha and oxidized phospholipids
Arteriosclerosis, thrombosis, and vascular biology. ,
2001; 21(10):
1585-91.
Subbanagounder, G Leitinger, N Schwenke, DC Wong, JW Lee, H Rizza, C Watson, AD Faull, KF Fogelman, AM Berliner, JA
Determinants of bioactivity of oxidized phospholipids. Specific oxidized fatty acyl groups at the sn-2 position
Arteriosclerosis, thrombosis, and vascular biology. ,
2000; 20(10):
2248-54.
Lee, H Shi, W Tontonoz, P Wang, S Subbanagounder, G Hedrick, CC Hama, S Borromeo, C Evans, RM Berliner, JA Nagy, L
Role for peroxisome proliferator-activated receptor alpha in oxidized phospholipid-induced synthesis of monocyte chemotactic protein-1 and interleukin-8 by endothelial cells
Circulation research. ,
2000; 87(6):
516-21.
Pinderski Oslund, LJ Hedrick, CC Olvera, T Hagenbaugh, A Territo, M Berliner, JA Fyfe, AI
Interleukin-10 blocks atherosclerotic events in vitro and in vivo
Arteriosclerosis, thrombosis, and vascular biology. ,
1999; 19(12):
2847-53.
Leitinger, N Tyner, TR Oslund, L Rizza, C Subbanagounder, G Lee, H Shih, PT Mackman, N Tigyi, G Territo, MC Berliner, JA Vora, DK
Structurally similar oxidized phospholipids differentially regulate endothelial binding of monocytes and neutrophils
Proceedings of the National Academy of Sciences of the United States of America. ,
1999; 96(21):
12010-5.
Subbanagounder G, Leitinger N, Shih PT, Faull KF, Lee H and Berliner JA.
Evidence that phospholipid oxidation products and/or platelet activating factor play an important role in early atherogenesis: In vitro and in vivo inhibition by WEB 2086,
Circ Res,
1999; 85:
311-318.
Honda HM, Leitinger N, Frankel M, Goldhaber JI, Natarajan R, Weiss JN, Nadler J and Berliner JA.
Induction of monocyte binding to endothelial cells by MM-LDL: the role of lipoxygenase metabolies,
Arterio Throm and Vasc Biol,
1999; 19:
680-686.
Rizza C, Leitinger N, Junming Y, Fischer DJ, Wang D, Shih PT, Lee H, Tigyi G and Berliner JA
Lysophosphatidic acid as a regulator of endothelial/leukocyte interaction,
Lab Invest,
1999; 79:
1227-1235.
Shih PT, Elices MJ, Fang ZT, Ugarova TP, Strahl D, Territo MC, Frank JS, Kovach NL, Cabanas C, Berliner JA and Vora DK.
MM-LDL induces monocyte adhesion to endothelial CS-1 by activating Beta 1 integrin,
J Clin Invest,
1999; 103:
613-625.
Leitinger N, Watson AD, Hama SY, Ivandic B, Qiao J, Huber J, Faull KF, Grass DS, Navab M, Fogelman AM, DeBeer F, Lusis A and Berliner JA.
Rose of Group II secretory PLA2 in atherosclerosis,
Arterio Throm and Vasc Biol,
1999; 19:
1291-1298.
Honda, HM Leitinger, N Frankel, M Goldhaber, JI Natarajan, R Nadler, JL Weiss, JN Berliner, JA
Induction of monocyte binding to endothelial cells by MM-LDL: role of lipoxygenase metabolites
Arteriosclerosis, thrombosis, and vascular biology. ,
1999; 19(3):
680-6.
Watson AD, Leitinger N ....and Berliner JA
Identification by Mass Spectrometry of Oxidized phospholipids in minimally oxidized LDL that induce monoocyte/endothelial intereactions and evidence for their presence in vivo,
J Biol Chem,
1997; 272:
13597-13607.
Watson AD, Leitinger N, Navab M, Faull KF, Horkko S, Witztum JL, Palinski W, Schwenke D, Salomon RG, Sha W, Subbanagounder G, Fogelman AM and Berliner JA.
Structual Identification by mass spectrometry of oxidized phospholipids in minimally oxidized LDL that induce monocyte/endothelial interactions and evidence for their presence in vivo,
J. Biol Chem,
1997; 272:
13597-13607.
Vora, DK Fang, ZT Liva, SM Tyner, TR Parhami, F Watson, AD Drake, TA Territo, MC Berliner, JA
Induction of P-selectin by oxidized lipoproteins. Separate effects on synthesis and surface expression
Circulation research. ,
1997; 80(6):
810-8.