The Mary S. Easton Center for Alzheimer's Disease Research at UCLA (UCLA-Easton Center) is a comprehensive research center focused on Alzheimer's disease (AD) and other dementias. The Center is named in honor of the mother of Jim Easton, a UCLA benefactor and partner to the Center. Jim lost his mother to AD. The theme of the Center is the therapeutic imperative, focusing on the overwhelming need for earlier (pre-dementia) diagnosis and new therapeutic agents that slow the course of AD and other dementias. Included in this theme is basic science study of the basic brain processes involved in AD, animal models of AD, clinical research of biomarkers for these diseases, diagnostic research, and clinical trials of new medications. The UCLA-Easton Alzheimer's Center is one of the top in the nation and is supported by the National Institutes on Aging, the State of California and generous donors who share our commitment to developing new therapies for AD.